ID 61267
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Nishimura, Yoshito Department of General Medicine, Okayama University Hospital ORCID publons researchmap
Hagiya, Hideharu Department of General Medicine, Okayama University Hospital ORCID Kaken ID researchmap
Obika, Mikako Department of General Medicine, Okayama University Hospital ORCID Kaken ID publons researchmap
Otsuka, Fumio Department of General Medicine, Okayama University Hospital ORCID Kaken ID publons researchmap
Abstract
Septic pulmonary embolism (SPE) is a rare yet serious infectious disorder with nonspecific clinical findings due to microorganism-containing emboli disseminating from extrapulmonary infectious foci. It is unknown whether a positive blood culture correlates with a worse clinical outcome. We compared the clinical and microbiologic characteristics of patients with SPE divided into the culture-positive group and the culture-negative one. This study was a retrospective observational study of the patients diagnosed with SPE and treated in an academic hospital from April 2010 to May 2020. We identified six culture-positive and four culture-negative patients with SPE during the study period. The culture-positive group had significantly longer periods of hospitalization (median: 75 days, range: 45-125 days) than the culture-negative group (median: 14.5 days, range: 3-43 days) (p < 0.05), as well as significantly elevated serum C-reactive protein and procalcitonin. Patients with culture-negative SPE more commonly had odontogenic infections as the primary infectious foci. Our study highlights the importance of giving extra attention to SPE patients who have a positive blood culture, as they may have worse clinical outcomes. Physicians need to collaborate with dentists when faced with patients with culture-negative SPE, since they may have primary odontogenic infections.
Keywords
septic pulmonary embolism
blood culture
procalcitonin
Published Date
2020-11-27
Publication Title
Pathogens
Volume
volume9
Issue
issue12
Publisher
MDPI
Start Page
995
ISSN
2076-0817
Content Type
Journal Article
language
英語
OAI-PMH Set
岡山大学
Copyright Holders
© 2020 by the authors.
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DOI
Web of Science KeyUT
Related Url
isVersionOf https://doi.org/10.3390/pathogens9120995
License
http://creativecommons.org/licenses/by/4.0/