ID 57491
FullText URL
Author
Ueda, Masashi Graduate School of Medicine, Dentistry, and Pharmaceutica Science, Okayama University ORCID Kaken ID publons researchmap
Yamagami, Daiki Graduate School of Medicine, Dentistry, and Pharmaceutica Science, Okayama University
Watanabe, Keiko Graduate School of Medicine, Dentistry, and Pharmaceutica Science, Okayama University
Mori, Asami Radioisotope Research Center, Kyoto University
Kimura, Hiroyuki Radioisotope Research Center, Kyoto University
Sano, Kohei Graduate School of Pharmaceutical Sciences, Kyoto University
Saji, Hideo Graduate School of Pharmaceutical Sciences, Kyoto University
Ishikawa, Kenji Graduate School of Engineering, Nagoya University
Hori, Masaru Graduate School of Engineering, Nagoya University
Sakakita, Hajime National Institute of Advanced Industrial Science and Technology
Ikehara, Yuzuru National Institute of Advanced Industrial Science and Technology
Enomoto, Shuichi Graduate School of Medicine, Dentistry, and Pharmaceutica Science, Okayama University Kaken ID publons researchmap
Abstract
The objective of this study is to examine the invasiveness of hemostasis by non-thermal plasma (NTP) compared with hemostasis by thermal coagulation (TC). The inflammation recovery process after hemostasis by TC and NTP was compared by using histological methods and nuclear medical molecular imaging. The necrotic areas in the NTP group disappeared after 5 days, whereas they remained 15 days after hemostasis in the TC group. The accumulation of 2-deoxy-2-[F-18] fluoro-D-glucopyranose (F-18-FDG), which reflects the existence of inflammatory cells, was higher in the TC group than in the NTP group on day 15. Thus, this study indicates that hemostasis by NTP is less inflammatory than TC. This report is the first to evaluate inflammation that occurred after hemostasis with medical devices noninvasively.
Keywords
hemostasis
imaging
inflammation
non-thermal plasma
positron emission tomography
Published Date
2015-09-28
Publication Title
Plasma Processes and Polymers
Volume
volume12
Issue
issue12
Start Page
1338
End Page
1342
ISSN
16128850
NCID
AA11976237
Content Type
Journal Article
language
英語
OAI-PMH Set
岡山大学
File Version
author
DOI
Web of Science KeyUT
Related Url
isVersionOf https://doi.org/10.1002/ppap.201500099
Funder Name
Japan Society for the Promotion of Science
助成番号
25108508
15H00895