ID 57116
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Kondo, Hideki Institute of Plant Science and Resources (IPSR), Okayama University Kakenhi
Chiba, Sotaro Asian Satellite Campuses Institute, Nagoya University
Maruyama, Kazuyuki Institute of Plant Science and Resources (IPSR), Okayama University
Andika, Ida Bagus Institute of Plant Science and Resources (IPSR), Okayama University
Suzuki, Nobuhiro Institute of Plant Science and Resources (IPSR), Okayama University
Abstract
Insects are the host and vector of diverse viruses including those that infect vertebrates, plants, and fungi. Recent wide-scale transcriptomic analyses have uncovered the existence of a number of novel insect viruses belonging to an alphavirus-like superfamily (virgavirus/negevirus-related lineage). In this study, through an in silico search using publicly available insect transcriptomic data, we found numerous virus-like sequences related to insect virga/nege-like viruses. Phylogenetic analysis showed that these novel viruses and related virus-like sequences fill the major phylogenetic gaps between insect and plant virga/negevirus lineages. Interestingly, one of the phylogenetic clades represents a unique insect-infecting virus group. Its members encode putative coat proteins which contained a conserved domain similar to that usually found in the coat protein of plant viruses in the family Virgaviridae. Furthermore, we discovered endogenous viral elements (EVEs) related to virga/nege-like viruses in the insect genomes, which enhances our understanding on their evolution. Database searches using the sequence of one member from this group revealed the presence of EVEs in a wide range of insect species, suggesting that there has been prevalent infection by this virus group since ancient times. Besides, we present detailed EVE integration profiles of this virus group in some species of the Bombus genus of bee families. A large variation in EVE patterns among Bombus species suggested that while some integration events occurred after the species divergence, others occurred before it. Our analyses support the view that insect and plant virga/nege-related viruses might share common virus origin(s).
Keywords
Bumblebee
Endogenous viral element
Evolution
Insect
Plant alpha-like virus
Transcriptome shotgun assembly
Whole genome shotgun assembly
Published Date
2019-03-31
Publication Title
Virus Research
Volume
volume262
Publisher
Elsevier Science
Start Page
37
End Page
47
ISSN
01681702
NCID
AA10642076
Content Type
Journal Article
language
英語
OAI-PMH Set
岡山大学
Copyright Holders
© 2017 Elsevier B.V. All rights reserved.
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isVersionOf https://doi.org/10.1016/j.virusres.2017.11.020
Citation
Hideki Kondo, Sotaro Chiba, Kazuyuki Maruyama, Ida Bagus Andika, Nobuhiro Suzuki, A novel insect-infecting virga/nege-like virus group and its pervasive endogenization into insect genomes, Virus Research, Volume 262, 2019, Pages 37-47, ISSN 0168-1702, https://doi.org/10.1016/j.virusres.2017.11.020.
Funder Name
Japanese Ministry of Education, Culture, Sports, Sciences and Technology (MEXT) (KAKENHI)
助成番号
15K07312 : メタゲノム解析に基づく菌類ウイルス叢の解明と有効利用に関する研究
16H06436 : 糸状菌ウイルスのネオ・ライフスタイル
16H06429 : ネオウイルス学:生命の源流から超個体、そしてエコ・スフィアーへ
16K21723 : 「ネオウイルス学」の国際活動支援
Open Access (Publisher)
non-OA
Open Archive (publisher)
Non-OpenArchive