ID 56074
JaLCDOI
FullText URL
72_3_283.pdf 2.28 MB
Author
Namba, Shihoko Center for Innovative Clinical Medicine, Okayama University Hospital
Ikeda, Fusao Department of Gastroenterology and Hepatology,Okayama University Hospital
Takaguchi, Koichi Department of Internal Medicine, Kagawa Prefectural Central Hospital
Shimomura, Yasuyuki Department of Gastroenterology and Hepatology,Okayama University Hospital
Yasunaka, Tetsuya Department of Gastroenterology and Hepatology,Okayama University Hospital
Okada, Hiroyuki Department of Gastroenterology and Hepatology,Okayama University Hospital
Abstract
We investigated whether a small amount of blood collected by fingertip blood sampling would be adequate in a mass examination for hepatitis virus infection in Japan. A cross-sectional survey was conducted at health fairs in Kasaoka City and Shodoshima Island, where participants took the hepatitis screening test. A total of 114 consecutive individuals who took the hepatitis screening test were enrolled. Twenty microliters of plasma was successfully obtained from all participants. Among the participants, two had positive results for HBs antigen and two were positive for anti-HCV; all four were > 60 years old and rarely visited the hospital. Thirty-three and 38 patients chronically infected with HBV and HCV, respectively, were examined for confirmatory assays at participating hospitals. All subjects with undetectable serum levels of HBs antigen and anti-HCV had undetectable levels of both markers in fingertip blood, and the levels in serum and fingertip blood were significantly correlated (p<0.01). The lower detection limit of HBs antigen was defined as 0.005 IU/ml, and the cut-off value of anti-HCV was 1.0 by using 10-μl fingertip blood samples. The fingertip blood sampling described herein may be adequate in mass examinations for hepatitis virus testing in Japan.
Keywords
fingertip
hepatitis test
HBV
HCV
Japan
Amo Type
Original Article
Published Date
2018-06
Publication Title
Acta Medica Okayama
Volume
volume72
Issue
issue3
Publisher
Okayama University Medical School
Start Page
283
End Page
287
ISSN
0386-300X
NCID
AA00508441
Content Type
Journal Article
language
英語
Copyright Holders
CopyrightⒸ 2018 by Okayama University Medical School
File Version
publisher
Refereed
True
PubMed ID