ID | 55853 |
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Author |
Okura, Tomohiro
Department of Residency Program, Okayama Saiseikai General Hospital
Fujii, Masakuni
Department of Internal Medicine, Okayama Saiseikai General Hospital
Shiode, Junji
Department of Internal Medicine, Okayama Saiseikai General Hospital
Ito, Yuri
Department of Surgery, Okayama Saiseikai General Hospital
Kojima, Toru
Center for Cancer Control and Statistics, Osaka Medical Center for Cancer and Cardiovascular Diseases
Nasu, Junichiro
Department of Internal Medicine, Okayama Saiseikai General Hospital
Niguma, Takefumi
Center for Cancer Control and Statistics, Osaka Medical Center for Cancer and Cardiovascular Diseases
Yoshioka, Masao
Department of Internal Medicine, Okayama Saiseikai General Hospital
Mimura, Tetsushige
Center for Cancer Control and Statistics, Osaka Medical Center for Cancer and Cardiovascular Diseases
Yamamoto, Kazuhide
Department of Internal Medicine, Okayama Saiseikai General Hospital
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Abstract | The impact of body mass index (BMI) on postoperative survival in Japanese patients with pancreatic cancer is unclear. We examined the relationship between preoperative BMI and the prognosis of Japanese patients who underwent surgery for pancreatic cancer to determine whether BMI affects these patients’ prognosis. Of the patients who underwent pancreatectomy between January 2004 and August 2015 at our institution, 246 were pathologically diagnosed with pancreatic tubular adenocarcinoma; the cancer was located in the pancreatic head (n=161) and in the body and tail (n=85). We classified the patients by BMI: underweight (n=22), normal weight (n=190), and overweight/obese (n=34) groups. We retrospectively analyzed medical records for patient characteristics, lesion location, disease stage, postoperative complications, chemotherapy, and prognosis. Lesion location, disease stage, postoperative complications, and chemotherapy were not significantly different among the BMI groups. The median survival times were as follows (days): all patients, 686; underweight, 485; normal weight, 694; and overweight/obese, 839. In a multivariate analysis, after adjusting for competing risk factors, low BMI was associated with an increased risk of death (normal weight: HR 0.58, p=0.038; overweight/obese: HR 0.54, p=0.059). High BMI was not found to be a postoperative factor for poor prognosis in Japanese pancreatic cancer patients.
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Keywords | pancreatic cancer
BMI
prognosis
surgery
risk factor
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Amo Type | Original Article
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Publication Title |
Acta Medica Okayama
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Published Date | 2018-04
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Volume | volume72
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Issue | issue2
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Publisher | Okayama University Medical School
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Start Page | 129
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End Page | 135
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ISSN | 0386-300X
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NCID | AA00508441
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Content Type |
Journal Article
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language |
English
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Copyright Holders | CopyrightⒸ 2018 by Okayama University Medical School
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File Version | publisher
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Refereed |
True
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PubMed ID |