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ID 54618
Title Alternative
Probable IgG4-related thyroiditis with cervical lymphadenopathy
Author
Kobashi, Kenta Department of Surgery, Saiseikai Saijo Hospital
Ishii, Hiroshi Department of Surgery, Saiseikai Saijo Hospital
Nishiyama, Kanako Breast Center, Ehime University Hospital
Matsumi, Yuki Department of Surgery, Saiseikai Saijo Hospital
Hatano, Masahide Department of Surgery, Saiseikai Saijo Hospital
Fujiwara, Masamitsu Department of Surgery, Imabariishikaishimin Hospital
Kurokawa, Tatsuo Department of Surgery, Saiseikai Saijo Hospital
Tsunemitsu, Kensuke Department of Surgery, Saiseikai Saijo Hospital
Abstract
 We present a case of probably IgG4-related thyroiditis with lymphadenopathy. The patient was a 70-year-old Japanese female who was undergoing hemodialysis and had undergone a right hemi-thyroidectomy in 1989 due to carcinoma. In December 2010, an ultrasonography study revealed a hypoechoic small lesion in thyroid gland. When the patient was admitted to our hospital in November 2013, the lesion and regional lymph nodes had enlarged and we suspected that they were metastatic thyroid cancer. We performed a residual total thyroidectomy and regional lymph node dissection in August 2014. At that time, lymphoplasmacytic infiltration and fibrosis were observed histopathologically in thyroid tissue. Immunohistochemical studies revealed infiltrated lymphocytes and plasma cells were markedly IgG-positive, and the ratio of IgG4-positive to IgG-positive cells was over 40%. We therefore diagnosed the patient with IgG4-related thyroiditis. The cervical lymph nodes were metastases of papillary carcinoma from 25 years earlier. The patient remains well without any recurrences 33 months after the surgery.
Keywords
IgG4 関連甲状腺炎(IgG4-related thyroiditis)
橋本病(Hashimoto’s thyroiditis)
転移性リンパ節腫瘍(metastatic lymph node tumor)
慢性腎不全(chronic renal failure)
Note
症例報告(Case Reports)
Published Date
2016-12-01
Publication Title
Journal of Okayama Medical Association
Publication Title Alternative
Journal of Okayama Medical Association
Volume
volume128
Issue
issue3
Publisher
岡山医学会
Publisher Alternative
Okayama Medical Association
Start Page
213
End Page
216
ISSN
0030-1558
NCID
AN00032489
Content Type
Journal Article
Official Url
http://www.okayama-u.ac.jp/user/oma/
language
日本語
Copyright Holders
Copyright (c) 2016 岡山医学会
File Version
publisher
Refereed
True
Eprints Journal Name
joma