ID 53671
JaLCDOI
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Author
Nojima, Daisuke
Fujimoto, Nobukazu
Kato, Katsuya
Fuchimoto, Yasuko
Kiura, Katsuyuki Kaken ID researchmap
Kishimoto, Takumi
Abstract
We investigated the clinical features of asbestos-induced diffuse pleural thickening (DPT) with severe respiratory compromise. We conducted a retrospective study of consecutive subjects with asbestos-induced DPT. Medical data such as initial symptoms, radiological findings, respiratory function test results, and clinical course were collected and analyzed. There were 24 patients between 2003 and 2012. All were men, and the median age at the development of DPT was 74 years. The top occupational category associated with asbestos exposure was dockyard workers. The median duration of asbestos exposure was 35.0 years, and the median latency from first exposure to the onset of DPT was 49.0 years. There were no significant differences in respiratory function test results between the higher and lower Brinkman index groups or between unilateral and bilateral DPT. Thirteen patients had a history of benign asbestos pleural effusion (BAPE), and the median duration from pleural fluid accumulation to DPT with severe respiratory compromise was 28.4 months. DPT with severe respiratory compromise can develop after a long latency following occupational asbestos exposure and a history of BAPE.
Keywords
asbestos
pleural thickening
MRC dyspnea scale
respiratory function test
costophrenic angle
Amo Type
Original Article
Published Date
2015-10
Publication Title
Acta Medica Okayama
Volume
volume69
Issue
issue5
Publisher
Okayama University Medical School
Start Page
261
End Page
266
ISSN
0386-300X
NCID
AA00508441
Content Type
Journal Article
language
英語
Copyright Holders
CopyrightⒸ 2015 by Okayama University Medical School
File Version
publisher
Refereed
True
PubMed ID
Web of Science KeyUT