ID 53260
Sort Key
10
Title Alternative
Gene therapy using REIC/Dkk-3-encoding adenoviral vector for the treatment of malignant pleural mesothelioma
FullText URL
Thumnail 127_47.pdf 416 KB
Author
Keywords
悪性胸膜中皮腫
REIC/DKK-3
遺伝子治療
Note
特集 (Feature Articles)
Publication Title
岡山医学会雑誌
Published Date
2015-04-01
Volume
volume127
Issue
issue1
Publisher
岡山医学会
Publisher Alternative
Okayama Medical Association
Start Page
47
End Page
50
ISSN
0030-1558
NCID
AN00032489
Content Type
Journal Article
Related Url
http://www.okayama-u.ac.jp/user/oma/
OAI-PMH Set
岡山大学
language
日本語
Copyright Holders
Copyright (c) 2015 岡山医学会
File Version
publisher
Refereed
True
DOI
NAID
Eprints Journal Name
joma
References
1) Robinson B, Musk A, Lake R : Malignant Mesothelioma. Lancet (2005) 366, 397-408.
2) Robinson B, Lake R : Advances in Malignant Mesothelioma. N Engl J Med (2010) 353, 1591-1603.
3) Vogelzang N, Rusthoven J, Symanowski J, Denham C, Kaukel E, Ruffie P, Gatzemeier U, Boyer M, Emri S, Manegold C, Niyikiza C, Paoletti P : Phase Ⅲ Study of Pemetrexed in Combination With Cisplatin Versus Cisplatin alone With Malignant Pleural Mesothelioma. J Clin Oncol (2003) 21, 2636-2644.
4) Sterman DH, Recio A, Vachani A, Sun J, Cheung L, DeLong P, Amin KM, Litzky LA, Wilson JM, Kaiser LR, Albelda SM : Long-term follow-up of patients with malignant pleural mesothelioma receiving high-dose adenovirus herpes simplex thymidine kinase/ganciclovir suicide gene therapy. Clin Cancer Res (2005) 11, 7444-7453.
5) Sterman DH, Recio A, Carroll RG, Gillespie CT, Haas A, Vachani A, Kapoor V, Sun J, Hodinka R, Brown JL, Corbley MJ, Parr M, et al. : A phase I clinical trial of single-dose intrapleural IFN-beta gene transfer for malignant pleural mesothelioma and metastatic pleural effusions : high rate of antitumor immune responses. Clin Cancer Res (2007) 13, 4456-4466.
6) Sterman DH, Recio A, Haas AR, Vachani A, Katz SI, Gillespie CT, Cheng G, Sun J, Moon E, Pereira L, Wang X, Heitjan DF, et al. : A phase I trial of repeated intrapleural adenoviral-mediated interferon-beta gene transfer for mesothelioma and metastatic pleural effusions. Mol Ther (2010) 18, 852-860.
7) Sterman DH, Haas A, Moon E, Recio A, Schwed D, Vachani A, Katz SI, Gillespie CT, Cheng G, Sun J, Papasavvas E, Montaner LJ, et al. : A trial of intrapleural adenoviral-mediated Interferon-alpha2b gene transfer for malignant pleural mesothelioma. Am J Respir Crit Care Med (2011) 184, 1395-1399.
8) Mukherjee S, Haenel T, Himbeck R, Scott B, Ramshaw I, Lake RA, Harnett G, Phillips P, Morey S, Smith D, Davidson JA, Musk AW, et al. : Replication-restricted vaccinia as a cytokine gene therapy vector in cancer : persistent transgene expression despite antibody generation. Cancer Gene Ther (2000) 7, 663-670.
9) Tsuji T, Miyazaki M, Sakaguchi M, Inoue Y, Namba M : A REIC gene shows down-regulation in human immortalized cells and human tumor-derived cell lines. Biochem Biophys Res Commun (2000) 268, 20-24.
10) Tsuji T, Nozaki I, Miyazaki M, Sakaguchi M, Pu H, Hamazaki Y, Iijima O, Namba M : Antiproliferative activity of REIC/Dkk-3 and its significant down-regulation in non-small-cell lung carcinomas. Biochem Biophys Res Commun (2001) 289, 257-263.
11) Kurose K, Sakaguchi M, Nasu Y, Ebara S, Kaku H, Kariyama R, Arao Y, Miyazaki M, Tsushima T, Namba M, Kumon H, Huh NH : Decreased expression of REIC/Dkk-3 in human renal clear cell carcinoma. J Urol (2004) 171, 1314-1318.
12) Hayashi T, Asano H, Toyooka S, Tsukuda K, Soh J, Shien T, Taira N, Maki Y, Tanaka N, Doihara H, Nasu Y, Huh NH, et al. : DNA methylation status of REIC/Dkk-3 gene in human malignancies. J Cancer Res Clin Oncol (2012) 138, 799-809.
13) Abarzua F, Sakaguchi M, Takaishi M, Nasu Y, Kurose K, Ebara S, Miyazaki M, Namba M, Kumon H, Huh NH : Adenovirus-mediated overexpression of REIC/Dkk-3 selectively induces apoptosis in human prostate cancer cells through activation of c-Jun-NH2-kinase. Cancer Res (2005) 65, 9617-9622.
14) Sakaguchi M, Kataoka K, Abarzua F, Tanimoto R, Watanabe M, Murata H, Than SS, Kurose K, Kashiwakura Y, Ochiai K, Nasu Y, Kumon H, et al. : Overexpression of REIC/Dkk-3 in normal fibroblasts suppresses tumor growth via induction of interleukin-7. J Biol Chem (2005) 284, 14236-14244.
15) Watanabe M, Kashiwakura Y, Huang P, Ochiai K, Futami J, Li SA, Takaoka M, Nasu Y, Sakaguchi M, Huh NH, Kumon H : Immunological aspects of REIC/Dkk-3 in monocyte differentiation and tumor regression. Int J Oncol (2009) 34, 657-663.
16) Edamura K, Nasu Y, Takaishi M, Kobayashi T, Abarzua F, Sakaguchi M, Kashiwakura Y, Ebara S, Saika T, Watanabe M, Huh NH, Kumon H : Adenovirus-mediated REIC/Dkk-3 gene transfer inhibits tumor growth and metastasis in an orthotopic prostate cancer model. Cancer Gene Ther (2007) 14, 765-772.