ID 52315
Sort Key
1
Title Alternative
Cholecystokinin plays a novel protective role in diabetic kidney through anti-inflammatory actions on macrophages
FullText URL
Thumnail 126_1.pdf 2.51 MB
Author
Miyamoto, Satoshi
Miyasaka, Kyoko
Okada, Shinichi
Sasaki, Motofumi
Hirota, Daisho
Kajitani, Nobuo
Takatsuka, Tetsuharu
Nishishita, Shingo
Horiguchi Sato, Chikage
Funakoshi, Akihiro
Keywords
cholecystokinin
糖尿病性腎症
抗炎症作用
腎保護効果
Note
平成24年度岡山医学会賞総合研究奨励賞(結城賞)受賞論文 (The 2012 Okayama Medical Association Award)
Publication Title
岡山医学会雑誌
Published Date
2014-04-01
Volume
volume126
Issue
issue1
Publisher
岡山医学会
Publisher Alternative
Okayama Medical Association
Start Page
1
End Page
6
ISSN
0030-1558
NCID
AN00032489
Content Type
Journal Article
Related Url
http://www.okayama-u.ac.jp/user/oma/
OAI-PMH Set
岡山大学
language
日本語
Copyright Holders
Copyright (c) 2014 岡山医学会
File Version
publisher
Refereed
True
DOI
Eprints Journal Name
joma
References
1) Sugimoto H, Shikata K, Hirata K, Akiyama K, Matsuda M, Kushiro M, Shikata Y, Miyatake N, Miyasaka M, Makino H : Increased expression of intercellular adhesion molecule-1 (ICAM-1) in diabetic rat glomeruli : glomerular hyperfiltration is a potential mechanism of ICAM-1 upregulation. Diabetes (1997) 46, 2075-2081.
2) Okada S, Shikata K, Matsuda M, Ogawa D, Usui H, Kido Y, Nagase R, Wada J, Shikata Y, Makino H : Intercellular adhesion molecule-1-deficient mice are resistant against renal injury after induction of diabetes. Diabetes (2003) 52, 2586-2593.
3) Miyamoto S, Shikata K, Miyasaka K, Okada S, Sasaki M, Kodera R, Hirota D, Kajitani N, Takatsuka T, Kataoka HU, Nishishita S, Sato C, et al. : Cholecystokinin plays a novel protective role in diabetic kidney through anti-inflammatory actions on macrophage : anti-inflammatory effect of cholecystokinin. Diabetes (2012) 61, 897-907.
4) Rehfeld JF : Clinical endocrinology and metabolism. Cholecystokinin. Best Pract Res Clin Endocrinol Metab (2004) 18, 569-586.
5) Crawley JN, Corwin RL : Biological actions of cholecystokinin. Peptides (1994) 15, 731-755.
6) Meng AH, Ling YL, Zhang XP, Zhang JL : Anti-inflammatory effect of cholecystokinin and its signal transduction mechanism in endotoxic shock rat. World J Gastroenterol (2002) 8, 712-717.
7) Li S, Ni Z, Cong B, Gao W, Xu S, Wang C, Yao Y, Ma C, Ling Y : CCK-8 inhibits LPS-induced IL-1beta production in pulmonary interstitial macrophages by modulating PKA, p38, and NF-kappaB pathway. Shock (2007) 27, 678-686.
8) Lacourse KA, Lay JM, Swanberg LJ, Jenkins C, Samuelson LC : Molecular structure of the mouse CCK-A receptor gene. Biochem Biophys Res Commun (1997) 236, 630-635.
9) de Weerth A, Jonas L, Schade R, Schoneberg T, Wolf G, Pace A, Kirchhoff F, Schulz M, Heinig T, Greten H, von Schrenck T : Gastrin/cholecystokinin type B receptors in the kidney : molecular, pharmacological, functional characterization, and localization. Eur J Clin Invest (1998) 28, 592-601.
10) Xu SJ, Gao WJ, Cong B, Yao YX, Gu ZY : Effect of lipopolysaccharide on expression and characterization of cholecystokinin receptors in rat pulmonary interstitial macrophages. Acta Pharmacol Sin (2004) 25, 1347-1353.
11) Sanchez AP, Sharma K : Transcription factors in the pathogenesis of diabetic nephropathy. Expert Rev Mol Med (2009) 11, e13.
12) Takano Y, Yamauchi K, Hayakawa K, Hiramatsu N, Kasai A, Okamura M, Yokouchi M, Shitamura A, Yao J, Kitamura M : Transcriptional suppression of nephrin in podocytes by macrophages : roles of inflammatory cytokines and involvement of the PI3K/Akt pathway. FEBS Lett (2007) 581, 421-426.
13) Leon-Tamariz F, Verbaeys I, Van Boven M, De Cuyper M, Buyse J, de Witte P, Verbruggen A, Cokelaere M : Biodistribution and pharmacokinetics of PEG-10kDa-cholecystokinin-10 in rats after different routes of administration. Curr Drug Deliv (2010) 7, 137-143.