ID | 48138 |
FullText URL | |
Title Alternative | Pathological complete response of advanced gastric cancer with pyloric stenosis to neoadjuvant S-1/CDDP chemotherapy: A case report
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Author |
Nishizaki, Masahiko
Fujiwara, Yasuhiro
Chouda, Yasuhiro
Kanazawa, Takashi
Ninomiya, Motoki
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Abstract | A 59-year-old man with epigastric discomfort and anorexia was referred to our hospital. Endoscopy revealed a type 3 advanced gastric cancer with pyloric stenosis diagnosed as a poorly differentiated adenocarcinoma in the biopsy specimens. A gastrojejunal bypass operation was performed because of direct invasion to the pancreas. The patient was treated by three courses of neoadjuvant chemotherapy with S-1/CDDP. Follow-up abdominal CT scan revealed that the primary tumor had become smaller, suggesting that a partial response had been achieved. Distal gastrectomy with D2 lymphadenectomy was performed. The histopathological examination showed no residual cancer cells in the primary lesion or dissected lymph nodes. Final chemotherapy efficacy was evaluated as Grade 3. The patient was treated with S-1 for one year after the gastrectomy and lymphadenectomy and has been followed up for 18 months without evidence of recurrence.
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Keywords | 幽門狭窄 (pyloric stenosis)
進行胃癌 (advanced gastric cancer)
S-1/CDDP
術前化学療法 (neoadjuvant chemotherapy)
組織学的CR (pathological CR)
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Note | 症例報告(Case Report)
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Published Date | 2012-04-01
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Publication Title |
岡山医学会雑誌
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Publication Title Alternative | Journal of Okayama Medical Association
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Volume | volume124
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Issue | issue1
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Publisher | 岡山医学会
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Publisher Alternative | Okayama Medical Association
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Start Page | 63
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End Page | 66
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ISSN | 0030-1558
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NCID | AN00032489
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Content Type |
Journal Article
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Related Url | http://www.okayama-u.ac.jp/user/oma/
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language |
Japanese
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Copyright Holders | Copyright (c) 2012 岡山医学会
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File Version | publisher
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Refereed |
True
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DOI | |
Eprints Journal Name | joma
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