このエントリーをはてなブックマークに追加
ID 46799
FullText URL
Thumnail 40_1383.pdf 986 KB
Title Alternative
Study on the elimination of dyes from the kidneys
Author
Nisimaru, Yasuyosi
Abstract
In spite of the many investigations regarding the elimination of the several dyes from the blood from the kidneys, since Heidenhain, there is as far as I know still a lack of systhematic investigation in relation to the diffusibity of dyes. Hoping to fill up this gap I made the following experiments on toads (Bufo japonicus).Method.For my purpose I used the following dyes; Phenol-sulphone phthalein, picric acid, chrysoidin, bismarckbrown, auranin, pyronin, eosin, methylen blue, safranin, patent blue V., rhodamin, extra B., methylviolet, fuchsin, neutralred, alkali blue, indulin, kongored, indigocarmin, carmin extra B,. As a preminary experiment I measured the rate of diffusion of these dyes on the gelatin and agar. The following list is arranged in the descending order of the diffusion rate of the dyes.1. phenol-sulphone phtalein, 2. picric acid, 3. rhodamin, 4. patent blue V., 5. chrysoidin, 6. pyronin, 7. safranin, 8. eosin, 9. fuchsin, 10. bismarckbrown, 11. methylen blue, 12. methylviolet B., 13. carmin, 14. neutralred, 15. kongored, 16. alkaliblue, 17. indulin. Summary. 1) 1. picric acid, 2. phenol-sulphone phthalein, 3. rhodamin, 4. patent blue V., 5. chrysoidin, 6. pyronin, 7. safranin, 8. eosin, 9. fuchsin, 10. bismarckblown, 11. methylen blue, 12. methylviolet, 13. carmin,. The above mentioned dyes are very easily eliminaten from the glomerular capsules but from the tubles the elimination is less in amount and the order is the one indicated above. 2) Neutralred, indulin, alkali blue and kongored are eliminated from the glomerular capsules, but not from the tubles. 3) The more elimination of dyes from the tubles abounds the greater is the diffusion. 4) When perfused from the renal portal vein only, the dyes were eliminated in the lumen, but there was either no elimination of water at all or it had been absorbed by the epithelium of the convoluted tubles. 5) The elimination of the dyes from the glomerular capsules is influenced neither by the supply of oxygen in the fluid-flow nor by poisoning with cyanic acid. The elimination of dyes is not always accompanied by oxydation. 6) The elimination of the dyes from the tubles is influenced both by th supply of oxygen in the fluid-flow, and by poisoning with cyanic acid, and elimination of the dyes is accompanied by oxydation. Accordingly, I summarize as follows.The glomerural capsules allow the diffusion into them of all the dyes, which were made use of in the experiments; and regarding the elimination of dyes from the tubles there can hardly be found an explanation in terms of physical chemistory.
Note
原著
Published Date
1928-07-31
Publication Title
岡山医学会雑誌
Volume
volume40
Issue
issue7
Publisher
岡山医学会
Start Page
1383
End Page
1401
ISSN
0030-1558
NCID
AN00032489
Content Type
Journal Article
Official Url
https://www.jstage.jst.go.jp/article/joma1889/40/7/40_7_1383/_article/-char/ja/
Related Url
http://www.okayama-u.ac.jp/user/oma/
language
日本語
Copyright Holders
Copyright© 岡山医学会
File Version
publisher
Refereed
True
Eprints Journal Name
joma