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ID 42755
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Title Alternative
Studies on the Virulence and Immunity of Newly Isolated Rickettsia Tsutsugamushi Strains I. Susceptibility of mouse and embryonated egg
Author
Nakayama, Tadao
Abstract
The auther carried out the experiments on the susceptibility of the mouse and embryonated egg to the strains of R. tsutsugamushi newly isolated in the various areas of Kagawa prefecture of japan. where "Umayado disease" and its suspected cases had been prevailing. The results are as follows: 1. The mouse shows greater susceptibility to the R. tsutsugamushi strains isolated in Kagawa prefecture than to the other reported ones. sometimes, however, it is not always infected according to the routs of inoculation'and, among various methods, intraperitoneal and intracranial inoculation are better methods becouse these take more stable infectious course, but it is necessary to change the methods according to the aim of experiment. 2. The mortality of the mice inoculated with this R. tsutsugamushi begins to rise from fifth day of inoculation, reachs the maximum on the twelveth or fourteenth day and then falls down. The rickettsiae, however, seems to stay in the bodies for a long time. 3. The susceptibility of the embyonated egg is very specific, namely the fixation and naturalization to it ability is different according to the sorts of strains. In the case where many riekettsiae are observable in yolk sack, LD50 is proved to be very high.
Published Date
1956-11-30
Publication Title
岡山医学会雑誌
Publication Title Alternative
Journal of Okayama Medical Association
Volume
volume68
Issue
issue11
Publisher
岡山医学会
Publisher Alternative
Okayama Medical Association
Start Page
2093
End Page
2102
ISSN
0030-1558
NCID
AN00032489
Content Type
Journal Article
Official Url
https://www.jstage.jst.go.jp/article/joma1947/68/11/68_11_2093/_article/-char/ja/
Related Url
http://www.okayama-u.ac.jp/user/oma/
language
日本語
Copyright Holders
Copyright© 岡山医学会
File Version
publisher
Refereed
True
Eprints Journal Name
joma