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ID 42754
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Title Alternative
Studies on the metabolism of Rickettsia
Author
Nakayama, Tadao
Abstract
The auther tried the partial purification of rickettsiae proliferated in the embryonated egg yolk sacks, and measured the respiration of these partially purified rickettsiae by the usual manometric technique. The results are as follows: 1. By partial purification, it was possible to obtain more purified and not inactivated rickettsiae. 2. As a result of oxygen consumption measurement with Warburg manometer, glutamate, succinate and aspartate were strongly oxidized, and, at the same time, α-ketoglutarate, fumarate, malate, oxaloacetate, pyruvate and β-glycerophosphate were also oxidized pretty well. 3. All enzymic inhibitors showed some inhibition, of which most remarkable was that by monoiodoacetate. 4. The inhibitive action of various antibiotics is varied according to their concentration. However, aureomycin proved to show always very remarkable inhibition. 5. Though incomplete, Rickettsia tsutsugamushi has its proper metabolic system, and is inferred to keep its proliferation by completing its metabolic system in support or connection with living cells
Published Date
1956-11-30
Publication Title
岡山医学会雑誌
Publication Title Alternative
Journal of Okayama Medical Association
Volume
volume68
Issue
issue11
Publisher
岡山医学会
Publisher Alternative
Okayama Medical Association
Start Page
2083
End Page
2092
ISSN
0030-1558
NCID
AN00032489
Content Type
Journal Article
Official Url
https://www.jstage.jst.go.jp/article/joma1947/68/11/68_11_2083/_article/-char/ja/
Related Url
http://www.okayama-u.ac.jp/user/oma/
language
日本語
Copyright Holders
Copyright© 岡山医学会
File Version
publisher
Refereed
True
Eprints Journal Name
joma