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ID 42746
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Thumnail 68_1981.pdf 375 KB
Title Alternative
On Inorganic Salt content in the Cat's Brain with Latent Cerebral Local Anaphylaxis. PART Ⅱ. Natrium, magnesium and chlorine contents in the cat's brain with latent cerebral local anaphylaxis.
Author
Namba, Tatsuji
Yamada, Minoru
Nakazawa, Takeshi
Okada, Yoshio
Nakayama, Akitoshi
Yoshikaya, Kiyoshi
Kimura, Takashi
Maeda, Akira
Shiromoto, Tetsuzo
Abstract
The toxicity of emulsified methylparathion was examined in comparison with ethylparathion. i) The LD(50) of methylparathion given orally to mice was 19.4-30.5 mg/kg and its mean value was 25.4mg/kg. (LD(50) of ethylparathion was 11.5mg/kg) The approximate LD(50) of methylparathion (ethylparathion) for the rabbit was 40-50 (8-10) by subcutaneous injection, 50-60 (20) by oral route and 200-400 (50-100) by dermal application. Thus, methylparathion was about 1/2-1/3 as toxic as ethylparathion. ii) The manifestations produced by methylparathion administration for rabbits were similar to those by ethylparathion. In addition, it was noted that the rabbits Ìn moderately poisoned cases were led to death after a week from malnutrition accompanied with anorexia and diarrhea. iii) The inhibitory action of methylparathion on the rabbit blood cholinesterase in vitro, was about 1/2-1/3 as great as that of ethylparathion. iv) In the laboratory rabbit there occurced leucocytosis, mainly occupied by pseudoeosinophils, and the deflection of Arneth count to the left as well as relative lymphocytopenia was observed.
Published Date
1956-11-30
Publication Title
岡山医学会雑誌
Publication Title Alternative
Journal of Okayama Medical Association
Volume
volume68
Issue
issue11
Publisher
岡山医学会
Publisher Alternative
Okayama Medical Association
Start Page
1981
End Page
1987
ISSN
0030-1558
NCID
AN00032489
Content Type
Journal Article
Official Url
https://www.jstage.jst.go.jp/article/joma1947/68/11/68_11_1981/_article/-char/ja/
Related Url
http://www.okayama-u.ac.jp/user/oma/
language
日本語
Copyright Holders
岡山医学会
File Version
publisher
Refereed
True
Eprints Journal Name
joma