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ID 42602
FullText URL
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Title Alternative
Studies on Parathion Poisoning Part 2. Parathion Poisoning in Experimental Liver Injury
Author
Tanimoto, Hajime
Abstract
Using the rabbits whose liver had been been injured with injection of 20% CCl(4) in oliveoil (1 cc/kg) every two days and administering parathion 24 hours after the third CCl(4) injection, the following results were obtained: 1) In rabbitts with injured liver serum cholinesterase activity reached its maximum 24 hours after the 3rd CCl(4) injection and returned to the original level, showing the improvement in the function of bromsulfalein excretion. 2) In the group with parathion injection 3 mg/kg each, serum cholinesterase activity was inhibited to the highest degree 3-6 hours after the parathion injection as in the healthy rabbits, but the slackening of cholinesterase activity in the injured was less marked than in the healthy, and lasted longer. 3) The LD(50) in the rabbits with injured liver was 3.88 (2.645.70) mg/kg, while the LD(50) in the healthy rabbits is 10 mg/kg. 4) In the injured rabbits parathion had no influence upon the recovery of the function of bromsulfalein excretion.
Published Date
1957-07-31
Publication Title
岡山医学会雑誌
Publication Title Alternative
Journal of Okayama Medical Association
Volume
volume69
Issue
issue7
Publisher
岡山医学会
Publisher Alternative
Okayama Medical Association
Start Page
1909
End Page
1914
ISSN
0030-1558
NCID
AN00032489
Content Type
Journal Article
Official Url
https://www.jstage.jst.go.jp/article/joma1947/69/7/69_7_1909/_article/-char/ja/
Related Url
http://www.okayama-u.ac.jp/user/oma/
language
日本語
Copyright Holders
Copyright© 岡山医学会
File Version
publisher
Refereed
True
Eprints Journal Name
joma