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ID 41068
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Title Alternative
Influences of Various Non-Essential Amino Acids on the Hematopoiesis Part 1. Influences of various non-essential amino acids on leucocyte growth in rabbit bone marrow tissue culture
Author
Lee, Bin Zen
Abstract
By adding such substances as polytamine, a derivative of amino acids (a by-product of caseous fermentation of cow's milk), by-product of cow's milk caseous hydrolysis with acid, and ten different non-essential amino acids contained in polytamine directly to rabbit bonemarrow tissue culture, the author estimated the tissue growth area and cell density and studied influences of these substances on the production of the leucocyte series in the bone marrow. The results are as follows. 1. Both polytamine and by-product of cow's milk caseous hydrolysis with acid can increase the growth area slightly more than the control only in a high concentration. 2. With addition of L-hydroxyproline in the concentration from 0.1 to 0.0001 per cent, this substance in any concentration within this range increases the growth area and cell density 2-3 times that of the control, showing the greatest values among amino acids used in the present experiment. 3. Both L-proline and L-arginine in high concentration increase the growth area twice the control, and slightly at low concentration. 4. L-Cysteine, L-tyrodine, and DL-serine each in a proximal concentration can only increase the growth area slightly more than the control. 5. L-Aspartic acid and L-glutamic acid, glycine, and L-ornithine show hardly any significant difference as compared with the control.
Published Date
1959-08-15
Publication Title
岡山医学会雑誌
Publication Title Alternative
Journal of Okayama Medical Association
Volume
volume71
Issue
issue8-2
Publisher
岡山医学会
Publisher Alternative
Okayama Medical Association
Start Page
5067
End Page
5078
ISSN
0030-1558
NCID
AN00032489
Content Type
Journal Article
Official Url
https://www.jstage.jst.go.jp/article/joma1947/71/8-2/71_8-2_5067/_article/-char/ja/
Related Url
http://www.okayama-u.ac.jp/user/oma/
language
日本語
Copyright Holders
岡山医学会
File Version
publisher
Refereed
True
Eprints Journal Name
joma