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ID 41011
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Title Alternative
On the Propagating Mechanism of Epileptic Convulsion and Blocking of Convulsion Part 1. Experimental studies on the propagating mechanism of epileptic Convulsion
Author
Funaki, Naoharu
Abstract
Epileptic convulsions were caused by local injection with metrazol in the motor cortex of cats. In each stadium after the onset of convulsions, resections of the motor cortex and lesions between the lenticular nucleus and the brain leg, between the lenticular nucleus and thalamus, between the black substance and red nucleus and between the black substance and peripheral parts was performed. Then the convulsions were continously recorded and investigated using electromyogram. The propagating mechanism was as follows: 1) The stimulation in the motor cortex provocated excitment in the lenticular nucleus and thalamus after a fixed time. Then after another fixed time the excitment in black substance and red nucleus was caused. It means that the excitment part mobilizes to the lower center with the elapse of time. 2) By the resection of the mortor cortex, the convulsions were able to be kept within 2 seconds after the onset of convulsions. Therefore the excitment in the lenticular nucleus and thalamus delayed 2 seconds more. 3) The resection between the lenticular nucleus and brain leg and the total resection between the leuticular nucleus and thalamus and between the black substance and red nucleus can inhibit the convulsion within 12 seconds after its onset. Therefore the excitment in the black substance and red nucleus delayed 12 seconds. 4) The lesion between the black substance and peripheral parts was able to inhibit the convulsions independently from time. It is regarded that, there are no centers in the lower parts, which are influenced by convulsions. 5) In order to have a long duration of the convulsions during a fixed time the the motor cortex must take in it.
Published Date
1959-07-10
Publication Title
岡山医学会雑誌
Publication Title Alternative
Journal of Okayama Medical Association
Volume
volume71
Issue
issue7-2
Publisher
岡山医学会
Publisher Alternative
Okayama Medical Association
Start Page
4451
End Page
4460
ISSN
0030-1558
NCID
AN00032489
Content Type
Journal Article
Official Url
https://www.jstage.jst.go.jp/article/joma1947/71/7-2/71_7-2_4451/_article/-char/ja/
Related Url
http://www.okayama-u.ac.jp/user/oma/
language
日本語
Copyright Holders
岡山医学会
File Version
publisher
Refereed
True
Eprints Journal Name
joma