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ID 41005
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Title Alternative
Experimental Studies on the Professional Allergic Skin Reactions induced by POCI(3) Part 1. Studies on the Serolochemical Properties of Phosphorylated Proteins
Author
Sato, Kazuto
Abstract
The author studied the serolochemical properties of phosphorylated proteins by POCI(3), that is, the cross-reactions of phosphorylated human serum albumin (PHuSa) with antibodies of phosphorylated crystalline hen's egg albumin (PEa) were observed by applying the precipitin tests (viz. the precipitin ring test and the serum agar precipitin test) and the active Arthus's test given to guinea pigs. And the following results were obtained. 1) PEa, when injected into rabbits, produced antibodies which gave precipitin reaction with PHuSa. However these anti-PEa sera also reacted both with PEa and unchanged egg albumin (Ea). 2) The anti-PEa sera reacted with PHuSa also by the Oudin's serum agar technic and it was presumed from this reaction that the PHuSa anti-PEa reaction was a single antigen antibody reaction system. 3) By increasing phosphoryl groups introduced into Ea, no remarkable changes given to the antigen titer of anti-PEa sera were found. 4) The PEa anti-PEa reaction was compared with the Ea anti-PEa reaction by applying the serum agar technic and the number of precipitate bands of the former was equal with that of the latter. But the moving speed of precipitate bands of the former was slow than that of the latter. 5) The Arthus's reaction between PHuSa and antibodies in guinea pigs actively sensitized to PEa was kypt positive, but as to these animals the Arthus's reactions with both PEa and Ea were also kept positive.
Published Date
1959-07-10
Publication Title
岡山医学会雑誌
Publication Title Alternative
Journal of Okayama Medical Association
Volume
volume71
Issue
issue7-2
Publisher
岡山医学会
Publisher Alternative
Okayama Medical Association
Start Page
4399
End Page
4410
ISSN
0030-1558
NCID
AN00032489
Content Type
Journal Article
Official Url
https://www.jstage.jst.go.jp/article/joma1947/71/7-2/71_7-2_4399/_article/-char/ja/
Related Url
http://www.okayama-u.ac.jp/user/oma/
language
日本語
Copyright Holders
岡山医学会
File Version
publisher
Refereed
True
Eprints Journal Name
joma