ID 31630
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Author
Yamamoto, Michinori
Takemoto, Mitsuhiro
Kuroda, Masahiro Kaken ID researchmap
Hiraki, Yoshio
Abstract
We analyzed the influence of various parameters on the results of radiotherapy for T1 glottic cancer by assessing the outcomes of 60 patients with this cancer who received definitive radiotherapy between 1985 and 1994. Seven patients were treated with a cobalt-60 unit, and the other 53 with a linear accelerator (26 patients at 3-MV, 10 at 6-MV, and 17 at 10-MV). Of the 17 patients treated at 10-MV, 4 also received part of their treatment with a cobalt-60 unit. The total radiation dose ranged from 56 Gy to 70 Gy (mean, 61 Gy). The total radiation dose of 51 patients (85%) was 60 Gy. The factors found to influence local control were the strength of the radiation beam energy and whether or not there was gross tumor invasion of the anterior commissure. The local control rate was 71% in the patients treated with a 10-MV linear accelerator, 56% in those treated with a 6-MV linear accelerator and, 97% in those treated with a cobalt-60 unit or a 3-MV linear accelerator (P = 0.0173). The local control rate was 43% in the patients with gross anterior commissure invasion and 88% in those without (P = 0.0075). We conclude that low energy photon beams are more suitable for the treatment of early glottic cancers, especially if the lesion grossly invades the anterior commissure.
Keywords
T1 glottic cancers
radiotherapy
radiation beam energy
Amo Type
Article
Published Date
1999-04
Publication Title
Acta Medica Okayama
Volume
volume53
Issue
issue2
Publisher
Okayama University Medical School
Start Page
91
End Page
94
ISSN
0386-300X
NCID
AA00508441
Content Type
Journal Article
language
英語
Copyright Holders
Copyright© 1999 Okayama University Medical School
File Version
publisher
Refereed
True
Web of Science KeyUT
Related Url
http://ousar.lib.okayama-u.ac.jp/metadata/3496