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ID 31216
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Author
Tai, Chiaki
Abstract

According to the data obtained in this experiment by means of the geldiffusion technique, the specific antigen was not detected in MH134 ascitic tumor, comparing the anti-C3H liver sera with anti-MH 134 tumor sera, though a loss of organ specific antigen and weak antigenicity were found in MH134 tumor extract. In order to detect some qualitative alteration, supposedly a gain in antigenic components, the transplant rejection test was carried out. The result of this test indicates that the relative not absolute resistance could be induced to C3H mice by this prior sensitization with cell free active extract eluted from MH134 tumor tissue by Fluorocarbon treatment. During these experiments, it became clear that MH134 ascitic tumor cell has weak immunizing properties so that prolonged lapse of time and large dose of antigen are inevitably necessary. Moreover, through Fluorocarbon treatment of the tumor homogenate, the cellfree, serologically active antigen could be obtained, which will serve well for the induction of the isologous immunization.

Published Date
1965-02
Publication Title
Acta Medicinae Okayama
Volume
volume19
Issue
issue1
Publisher
Okayama University Medical School
NCID
AA00041342
Content Type
Journal Article
language
英語
OAI-PMH Set
岡山大学
File Version
publisher
Refereed
True
Amo Type
Article
Submission Path
amo/vol19/iss1/4