このエントリーをはてなブックマークに追加
ID 30294
FullText URL
Author
Hiraki, K.
Ofuji, T.
Kobayashi, T.
Sunami, H.
Awai, K.
Abstract

The idiopathic thrombocytopenic purpura was described by Werlhof as an independent disease first in 1738. Kaznelson reported the excellent effect of splenectomy for its chronic type in 1915. For the genesis of its thrombocytopenia, there have been many theories to be concluded into the followings, 1) the development of an auto-immune mechanism resulting in platelet destruction, 2) increased platelet destruction in the spleen, 3) the inhibition of platelet production from the marrow megakaryocytes by a humoral factor produced in the spleen, 4) both increased destruction and decreased production of the platelet. Among the above four theories, the third one is the most popular in the chronic type.

Published Date
1956-04
Publication Title
Acta Medicinae Okayama
Volume
volume10
Issue
issue2
Publisher
Okayama University Medical School
NCID
AA00041342
Content Type
Journal Article
language
英語
OAI-PMH Set
岡山大学
File Version
publisher
Refereed
True
Amo Type
Article
Submission Path
amo/vol10/iss2/1