ID | 19562 |
Eprint ID | 19562
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FullText URL | |
Title Alternative | studies on the Pathogenic Agant of Infectious Hepatitis in Okayama Prefecture, Particularly on the Virus Isolated by the Embryonated Hen's Egg Ⅱ: Characters of the Isolated Virus
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Author |
Tawara, Jutaro
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Abstract | The author studied the virological characters of the virus isolated by the Chick-embryo technic, and obtained the following results: Inoculation of the virus into the chorio-allantoic cavity of the 7 day old chick-embryo killed the chick-embryo on the 5th to 7th day after inoculation. The serial passage could be carried out by inoculation of the chorio-allantoic fluid or the chick-embryo liver, of which the latter gave a better result. The amniotic inoculation could kill the chick-embryo on the 4th to 5th day after inoculation, but LD(50) was lower than that by the chorio-allantoic route. The yalk sack inoculation could not give a good result. As for the distribution of the virus by chorio-allantoic inoculation, the virus could be best proved in the chick-embryo, particularly in the liver, the next in the chorio-allantoic fluid and very few in the other parts. The isolated virus easily passed Seitz E. K., Berkefeld N. and also Berkefeld W., though somewhat difficult through the last one; this fact suggests that the isolated virus is pretty small one. Though the infectious index of the virus to the chick-embryo varied with the generations of the passage, the average for 10 to 20 generations was 8.0. The isolated virus could be well preserved in the glycerin-salt solution.
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Published Date | 1959-04-25
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Publication Title |
岡山医学会雑誌
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Publication Title Alternative | Journal of Okayama Medical Association
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Volume | volume71
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Issue | issue5-2
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Publisher | 岡山医学会
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Publisher Alternative | Okayama Medical Association
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Start Page | 2653
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End Page | 2659
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ISSN | 0030-1558
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NCID | AN00032489
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Content Type |
Journal Article
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Official Url | https://www.jstage.jst.go.jp/article/joma1947/71/5-2/71_5-2_2653/_article/-char/ja/
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Related Url | http://www.okayama-u.ac.jp/user/oma/
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language |
Japanese
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Copyright Holders | 岡山医学会
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File Version | publisher
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Refereed |
True
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Eprints Journal Name | joma
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