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ID 19489
Eprint ID
19489
FullText URL
71_2335.pdf 460 KB
Title Alternative
Experimental Study on Gastric Pepsin and Uropepsin Part Ⅲ. The Relation between Gastric Pepsin and Uropepsin in Rat
Author
Hayashi, Hiroshi
Abstract
1. The gastric juice of the adult rats, with histamine injection, with extirpation of endocrine organ, vagotomy and fracture of femur was collected respectively for 6 to 12 hours after pylorus-ligature. The samples were studied on quantity and peptic activity. The urine was collected for 24 hours after the same procedures and studied on uropepsin. 2. As a result of histamine injection, the peptic actvity of gastric secretion was slightly depressed. The peptic activity showed moderate depression with adrenalectomy, marked depression with hypophysectomy or adreno-hypophysectomy, some depression with vagotomy or thyreoidectomy, slight change with orchiectomy or oophorectomy and slight depression with fracture. On the other hand, the uropepsin level in urine showed no remarked change with histamine injection, decrease with adrenalectomy, moderate increase with hypophysectomy when the ample water was administered; slight decrease with vagotomy, no change with thyroidectomy, slight change with orchiectomy or oophorectomy and increase with fracture. 3. From the above experiments, it was concluded that the pepsinogen secretion into gastric lumen was not always parallel with its excretion into urine. It was suggested that there is some difference between the factors influencing upon the exocrine mechanism of the pepsinogen and those upon the endocrine mechanism.
Published Date
1959-04-15
Publication Title
岡山医学会雑誌
Publication Title Alternative
Journal of Okayama Medical Association
Volume
volume71
Issue
issue5-1
Publisher
岡山医学会
Publisher Alternative
Okayama Medical Association
Start Page
2335
End Page
2342
ISSN
0030-1558
NCID
AN00032489
Content Type
Journal Article
Official Url
https://www.jstage.jst.go.jp/article/joma1947/71/5-1/71_5-1_2335/_article/-char/ja/
Related Url
http://www.okayama-u.ac.jp/user/oma/
language
日本語
Copyright Holders
岡山医学会
File Version
publisher
Refereed
True
Eprints Journal Name
joma