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ID 19291
Eprint ID
19291
FullText URL
Thumnail 70_3931.pdf 10.3 MB
Title Alternative
Histological Study of Vital Organs under Experimental Hypothermia Part 1. Histochemical Study of Adrenal Cortex under Experimental Hypothermia with or without Cortisone & ACTH administration
Author
Takagi, Shigeru
Abstract
Histochemical studies of adrenal cortex of male rats under various hypothermic conditions: ice-water immersion with or without administration of Thiopental Sodium or Phenothiazine-derivatives, rewarming, surgical stress and Cortisone & ACTH administration were performed according to Dempsey's method. 1) Differences in individual were minimum and the respiration, circulation and the course of body temperature reduction were much stable under pharmacological hibernation. 2) Ketosteroids in fasciculata and reticularis zones of adrenal cortex were markedly depleted by cold application, but using anesthetics, especially on pharmadological hibernation, depletion of KS was less. 3) Hypothermia and pharmacological hibernation lessened the changes in adrenal cortex by operativ measures (partial resection of liver) under cooling. 4) Some circulatory and parenchimatous changes by cooling and rewarming were observed histologically in the adrenal cortex. Hemorrhagic changes were seen in the adrenal cortex after cooling to 20,5℃ of body temperature, but were less marked after administration of Phenothiazine-derivatives. 5) Cortisone or ACTH had some protective effects against reduction of weight and histlogical changes of adrenal cortex by cooling.
Published Date
1958-11-30
Publication Title
岡山医学会雑誌
Publication Title Alternative
Journal of Okayama Medical Association
Volume
volume70
Issue
issue11
Publisher
岡山医学会
Publisher Alternative
Okayama Medical Association
Start Page
3931
End Page
3950
ISSN
0030-1558
NCID
AN00032489
Content Type
Journal Article
Official Url
https://www.jstage.jst.go.jp/article/joma1947/70/11/70_11_3931/_article/-char/ja/
Related Url
http://www.okayama-u.ac.jp/user/oma/
language
日本語
Copyright Holders
岡山医学会
File Version
publisher
Refereed
True
Eprints Journal Name
joma