このエントリーをはてなブックマークに追加
ID 19181
Eprint ID
19181
FullText URL
Thumnail 71_779.pdf 385 KB
Title Alternative
Studies on Brain Hexokinase. Part Ⅰ. On hexokinase in the cerebral cortex of rabbits
Author
Yamada, Takahiko
Abstract
The hexokinase activity in the cerebral cortex of normal rabbits was measured by Longs method and the influences of fluoride, Ca ion, glutamic acid, glutamine, aspartic acid, asparagine, γ-aminobutyric acid and α-ketoglutaric acid upon the hexokinase activity were also evaluated. The results were as follows: 1) The fluoride shows the maximum inhibition to the hexokinase activity at 0.5M of its concentration, and the inhibition rather decreases at higher concentration. 2) Ca ion shows an increasing inhibition as its concentration increases. 3) When asparagine or glutamic acid is added, the activity is markedly accelerated. 4) γ-Aminobutyric acid accelerates slightly the activity of the cerebral hexokinase and markedly that of the heart muscle hexokinase. 5) α-Ketoglutaric acid markedly inhibits the activity.
Published Date
1959-02-28
Publication Title
岡山医学会雑誌
Publication Title Alternative
Journal of Okayama Medical Association
Volume
volume71
Issue
issue2-2
Publisher
岡山医学会
Publisher Alternative
Okayama Medical Association
Start Page
779
End Page
784
ISSN
0030-1558
NCID
AN00032489
Content Type
Journal Article
Official Url
https://www.jstage.jst.go.jp/article/joma1947/71/2-2/71_2-2_779/_article/-char/ja/
Related Url
http://www.okayama-u.ac.jp/user/oma/
language
日本語
Copyright Holders
岡山医学会
File Version
publisher
Refereed
True
Eprints Journal Name
joma