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ID 19121
Eprint ID
19121
FullText URL
Thumnail 71_527.pdf 2.53 MB
Title Alternative
Experimental Gastric Ulcer Induced by Hormonal Disharmony Part 1. On the influence of some factors upon gastric ulcer induced by adrenalectomy
Author
Tanabe, Kenichi
Abstract
Ulcer induced by adrenalectomy has been found in close relationships with abnormalities in blood components, particularly with inbalance in serum K and Na. When the abnormality of these blood components after adrenalectomy was corrected by oral administration of 1.0% NaCl solution, by substitution therapy utilizing adrenal cortical hormone (cortisone) or by vagotomy, ulcer could be prevented. However, the excessive substitution therapy was found to fail preventing the induction of ulcer, intramuscular administration of cortisone 5 mg/animal/day had failed to prevent the ulcer. But a formation of ulcer in adults rats could be prevented by oral administration of 1 % KCl with cortisone 5 mg/animal/day after adrenalectomy. Since the facts descrived above, it was concluded that inbalance of the blood components due to disharmony in adrenal cortical hormones resulted in weakening of the tissue resistance of gastric mucosa, which would be one of the most important factors in experimental gastric ulcer mentioned above. In this meaning, 1 called it as "gastric ulcer due to hormonal disharmony" and discussed in detail.
Published Date
1959-02-28
Publication Title
岡山医学会雑誌
Publication Title Alternative
Journal of Okayama Medical Association
Volume
volume71
Issue
issue2-1
Publisher
岡山医学会
Publisher Alternative
Okayama Medical Association
Start Page
527
End Page
541
ISSN
0030-1558
NCID
AN00032489
Content Type
Journal Article
Official Url
https://www.jstage.jst.go.jp/article/joma1947/71/2-1/71_2-1_527/_article/-char/ja/
Related Url
http://www.okayama-u.ac.jp/user/oma/
language
日本語
Copyright Holders
岡山医学会
File Version
publisher
Refereed
True
Eprints Journal Name
joma