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ID 19069
Eprint ID
19069
FullText URL
70_2381.pdf 472 KB
Title Alternative
Studies on the Bone Marrow Function and the Iron Metabolism Part 2. On the Iron Metabolism of Bone Marrow Cells
Author
Shiomi, Fumitoshi
Abstract
The uptake and utilization of radioactive iron by rabbit bone marrow cells under various conditions in vitro was studied, and the iron metabolism in bone marrow cells was discussed. The bone marrow cells were capable of taking up radioactive iron from media (physiological saline solution containing Fe(55) Cl(3)), and with an increase in the concentration of iron media the uptake increased to some extent. The greater part of the intracellular iron was reserved in the form binding with some proteins (?) and its capacity was greater than a sufficient amount of materials for heme synthesis. However, the capacity decreased in matured red cells. The incorporation of radioactive iron into heme increased constantly with the lapse of time and irrespective of the amount of the iron uptake. The large amount of intracellular non-hemin iron as well as the anerobic state caused inhibition for the heme synthesis.
Published Date
1958-07-31
Publication Title
岡山医学会雑誌
Publication Title Alternative
Journal of Okayama Medical Association
Volume
volume70
Issue
issue7
Publisher
岡山医学会
Publisher Alternative
Okayama Medical Association
Start Page
2381
End Page
2387
ISSN
0030-1558
NCID
AN00032489
Content Type
Journal Article
Official Url
https://www.jstage.jst.go.jp/article/joma1947/70/7/70_7_2381/_article/-char/ja/
Related Url
http://www.okayama-u.ac.jp/user/oma/
language
日本語
Copyright Holders
岡山医学会
File Version
publisher
Refereed
True
Eprints Journal Name
joma