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ID 19024
Eprint ID
19024
FullText URL
Thumnail 70_2069.pdf 6.23 MB
Title Alternative
Cytological Studies on the Explanted Bone Marrow Tissue by Stained Section Specimens Part 1. Explanted Bone Marrow Tissue of Normal Rabbit
Author
Hattori, Yoshiyuki
Abstract
In the observations carried on section specimens prepared from the explanted bone marrow tissue of normal rabbits, the following results were obtained: 1. In the regular culture method wandering cells, wandering out of the explanted bone marrow piece, form a growth zone and also cells without wandering capacity appear in the center of the growth zone. In culture immature bone-marrow cells reach maturity, and the mitotic index, having its peak at the 12-hour culture, fluctuates up and down. Namely, in the present study it has been clarified that not only bone marrow cells wander out but also maturation and mitosis take place in bone marrow culture. After 4-5 days' culture interstitial cells grow actively and also fibroblasts are observed to proliferate. 2. Vitamin B(12) helps to promote the mitosis and maturation of bone marrow cells. 3. Folic acid acts on bone marrow in the same manner as vitamin B(12) though to a lesser degree. 4. Nitoromin inhibits the mitosis of bone marrow cells and promotes the degeneration of granular leucocytes. 5. Carzinophilin like nitromin inhibits the mitosis and promotes the cell degeneration. 6. A simple tissue culture method is not simply for supravital observation, but it induces bone marrow cells to wander out, mature, and also induces mitosis although it is inferior to the regular method of tissue culture.
Published Date
1958-06-30
Publication Title
岡山医学会雑誌
Publication Title Alternative
Journal of Okayama Medical Association
Volume
volume70
Issue
issue6
Publisher
岡山医学会
Publisher Alternative
Okayama Medical Association
Start Page
2069
End Page
2080
ISSN
0030-1558
NCID
AN00032489
Content Type
Journal Article
Official Url
https://www.jstage.jst.go.jp/article/joma1947/70/6/70_6_2069/_article/-char/ja/
Related Url
http://www.okayama-u.ac.jp/user/oma/
language
日本語
Copyright Holders
岡山医学会
File Version
publisher
Refereed
True
Eprints Journal Name
joma