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ID 18664
Eprint ID
18664
FullText URL
Thumnail 72_1595.pdf 11.2 MB
Title Alternative
STUDIES ON TISSUE CULTURES OF HUMAN AND MOUSE TUMORS Part 3. Protein Metabolism of Human Cervical Carcinoma Bashford's Mouse Carcinoma, and Normal Mouse Liver Tissue in Tissue Culture
Author
Shiraishi, Akinori
Abstract
The protein metabolism of human cervical carcinoma, Bashford's mouse carcinoma, and normal mouse liver tissue have been studied with special reference to the culture media, and the following results were obtained. 1. The whole protein in the culture media of human cervical carcinoma, Bashford's mouse carcinoma, and normal mouse liver tissue was estimated. And as the results it was found that with lapse of time of the culture, human cervical carcinoma and Bashford's mouse carcinoma showed a higher protein consumption than that by normal mouse liver tissue. 2. In every tissue culture albumin was increased as compared with that in the control, but there was no difference between tumor tissues and normal tissue. 3. α-globulin in the media of human cervical carcinoma had no deviation from the control. α-globulin in the media of Bashford's mouse carcinoma showed a derease when compared with that of the control on one day after tissue cnlture, but with lapse of time in tissue culture it was increased. In the culture media of normal mouse liver tissue, α-globulin showed an increase as compared with the control on one day after tissue culture, but a remarkable decrease was found on 3 days afterward. As for normal mouse liver tissue, α-globulin showed the lower value than human cervical carcinoma and Bashford's mouse carcinoma during the course of tissue cultures. 4. The remarkable increase of β-globulin in the culture media of human cervical carcinoma could be seen. In the media of Bashford's mouse carcinoma, β-globulin showed a decrease on 3 days after tissue culture. β-globulin in the culture media of normal mouse liver tissue revealed an increase on one day after tissue culture, but on third day Bashford's mouse carcinoma and normal mouse liver tissue presented almost the same value. And both tissues showed an increase on five days cfter the tissue culture. 5. γ-globulin in every tissue culture was found to show a decrease as compared with the control along with the lapse of culture time. And in this respect no difference was found between tumor tissues and normal tissue.
Published Date
1960-10-30
Publication Title
岡山医学会雑誌
Publication Title Alternative
Journal of Okayama Medical Association
Volume
volume72
Issue
issue8-10
Publisher
岡山医学会
Publisher Alternative
Okayama Medical Association
Start Page
1595
End Page
1607
ISSN
0030-1558
NCID
AN00032489
Content Type
Journal Article
Official Url
https://www.jstage.jst.go.jp/article/joma1947/72/8-10/72_8-10_1595/_article/-char/ja/
Related Url
http://www.okayama-u.ac.jp/user/oma/
language
日本語
Copyright Holders
岡山医学会
File Version
publisher
Refereed
True
Eprints Journal Name
joma