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ID 18398
Eprint ID
18398
FullText URL
Thumnail 74_567.pdf 351 KB
Title Alternative
Experimental Study on Inhibition of the ep-Mouse Convulsion Part 1 Anti-convulsants and Their Effects on the ep-Mouse Convulsion
Author
Kasahara, Junzi
Abstract
Various dosages of glutamic acid, asparagine, GABA (γ-aminobutyric acid), GABOB (γ-amino-β-hydroxybutyric acid) and diphenylhydantoin each were given to the ep mouse once a day for 3 weeks and their effects on the convulsive seizure were compared. 1. Three week successive administration of various dosages, each of glutamic acid, asparagine, GABA and GABOB, could not inhibit convulsive seizure in the ep mouse. 2. In contrast, diphenylydantoin revealed to inhibit the convulsion: an absolute abolishment of the seizure was obtained a week, three days and 8 hours after the a ministration of 40-60, 80 and 100 mg/kg/day of diphenylhydantoin respectively. 3. The convulsive seizure in the ep mouse was found to recur within 6 days after the abstention of diphenylhydantoin administration.
Published Date
1962-07-30
Publication Title
岡山医学会雑誌
Publication Title Alternative
Journal of Okayama Medical Association
Volume
volume74
Issue
issue4-7
Publisher
岡山医学会
Publisher Alternative
Okayama Medical Association
Start Page
567
End Page
571
ISSN
0030-1558
NCID
AN00032489
Content Type
Journal Article
Official Url
https://www.jstage.jst.go.jp/article/joma1947/74/4-7/74_4-7_567/_article/-char/ja/
Related Url
http://www.okayama-u.ac.jp/user/oma/
language
日本語
Copyright Holders
岡山医学会
File Version
publisher
Refereed
True
Eprints Journal Name
joma