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ID 18361
Eprint ID
18361
FullText URL
Thumnail 74_307.pdf 5.44 MB
Title Alternative
Effect of unsaturated high fatty acid fraction extracted from X-ray irradiated rabbit liver (OX) on the mitochondrial swelling of normal rat liver
Author
Urakami, Hiroyuki
Abstract
The effects of OX, a high unsaturated fatty acid fraction extracted from x-ray irradiated rabbit liver, on rat liver mitochondrial swelling was studied and following results were obtained. 1) Strong swelling action is demonstrated at OX concentration above 0.001% in 0.15KCl solution. 2) Swelling action on mitochondria is reduced by sucrose but not changed by sodium succinate. On the other hand, serum albumin and ATP inhibit completely mitochondrial swelling. 3) Mitochondrial swelling caused by OX is reversed by serum albumin and ATP. The intensity of contraction is found in the following order containing ATP, ATP+Mg and ATP +Mg+serum in the media. 4) M itochondrial swelling is induced by 0.005% OX in the substrate of succinate but respiration is not largely prevented. 5) The incorporation of P(32) into Δ10P of swollen mitochondria is almost completely inhibited by OX.
Published Date
1962-03-30
Publication Title
岡山医学会雑誌
Publication Title Alternative
Journal of Okayama Medical Association
Volume
volume74
Issue
issue1-3
Publisher
岡山医学会
Publisher Alternative
Okayama Medical Association
Start Page
307
End Page
312
ISSN
0030-1558
NCID
AN00032489
Content Type
Journal Article
Official Url
https://www.jstage.jst.go.jp/article/joma1947/74/1-3/74_1-3_307/_article/-char/ja/
Related Url
http://www.okayama-u.ac.jp/user/oma/
language
日本語
Copyright Holders
岡山医学会
File Version
publisher
Refereed
True
Eprints Journal Name
joma