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ID 18195
Eprint ID
18195
FullText URL
Thumnail 80_1223.pdf 1.85 MB
Title Alternative
A Histochemical Study of Cytoplasmic Bodies in the Thymo-lymphatic Tissues of the mouse
Author
Ueki, Ayako
Asano, Kazuyuki
Ohmura, Morito
Osogoe, Bunsuke
Abstract
At the beginning of the 20th century, the cytoplasmic bodies which appear in the lymphoid tissues of mammals had received much attention of haematologists, in the relation to the origin of the blood platelets. However, since Wright described and figured in 1910 the process of cytoplasmic budding of megakaryocytes by the use of his own technics, the biological significance of the cytoplasmic bodies in the lymphoid tissues has been ignored until now. Recent works on the formation of antibodies in the lymphoid tissue seem to suggest, on the other hand, that these bodies would play an important role in the immune response. Consequently, we attended a renewed study of these bodies. In this paper we described the results of histochemical observations on these bodies in, the mesenteric lymph node and thymus of adult mice. The chief findings are as follows: 1. Cytoplasmic bodies are found in large number in the mesenteric lymph node of adult mice. They also occur in the thymus, though in much smaller numbers. 2. Cytoplasmic bodies in the thymolymphatic tissues vary greatly in size, from the size of blood platelets to that of small lymphocytes, and are commonly round in shape. They often contain pyroninophilic granules. 3. Staining of these bodies with methyl green-pyronin and acridine orange revealed that they contain abundant RNA. However, no evidence was obtained for the presence of DNA in these bodies. 4. After digestion of the samples with RNase, the pyroninophilia of these bodies disappeared completely. This suggests that the pyroninophilic granules of these bodies might be regarded as ribosomes.
Published Date
1968-12-30
Publication Title
岡山医学会雑誌
Publication Title Alternative
Journal of Okayama Medical Association
Volume
volume80
Issue
issue11-12
Publisher
岡山医学会
Publisher Alternative
Okayama Medical Association
Start Page
1223
End Page
1227
ISSN
0030-1558
NCID
AN00032489
Content Type
Journal Article
Official Url
https://www.jstage.jst.go.jp/article/joma1947/80/11-12/80_11-12_1223/_article/-char/ja/
Related Url
http://www.okayama-u.ac.jp/user/oma/index.html
language
日本語
Copyright Holders
岡山医学会
File Version
publisher
Refereed
True
Eprints Journal Name
joma