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ID 18145
Eprint ID
18145
FullText URL
Thumnail 80_803.pdf 12.9 MB
Title Alternative
Action of Drin Compounds on the Function of the Circulatory System Part 2. Action of Drin Compounds on the Frog Heart
Author
Hyodo, Kojiro
Abstract
By studying the action of drin compounds on isolated frog heart (Straub-Fuhner's method), the author obtained the following results: 1. In the case of dun compounds at a low concentration there occurs a slight decrease in the amplitude of heart beats. 2. At a high concentration, atrioventricular block and low amplitude are obserbed. Such changes are more prominent at a higher concentration, which eventually leads to diastolic cardiac arrest. 3. Premedicaticn of atropine does not reduce the suppressive action of dieldrin. 4. When atropine is given to the heart after exposure to dieldrin, an increase in the amplitude and continuance of heart beats may be seen. 5. Application of adrenaline previous to dieldrin, does not influence the decrease in the amplitude of heart beats. 6. When adrenaline is applied just prior to the cardiac arrest by dieldrin, heart beats are maintained with an increase of their amplitude. 7. It is concluded that drin compounds are not cholinesterase blockers such as alkylphosphates.
Published Date
1968-08-30
Publication Title
岡山医学会雑誌
Publication Title Alternative
Journal of Okayama Medical Association
Volume
volume80
Issue
issue7-8
Publisher
岡山医学会
Publisher Alternative
Okayama Medical Association
Start Page
803
End Page
813
ISSN
0030-1558
NCID
AN00032489
Content Type
Journal Article
Official Url
https://www.jstage.jst.go.jp/article/joma1947/80/7-8/80_7-8_803/_article/-char/ja/
Related Url
http://www.okayama-u.ac.jp/user/oma/
language
日本語
Copyright Holders
岡山医学会
File Version
publisher
Refereed
True
Eprints Journal Name
joma