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ID 18014
Eprint ID
18014
FullText URL
Thumnail 79_387.pdf 2.69 MB
Title Alternative
Experimental Studies on the Influence of Surgical Intervention on the Metabolism of Retlculoendothelial System Ⅲ. An Experimental Study on the Examination of RESfunction by Lipid Colloids
Author
Fujisawa, Masahiko
Abstract
In an attempt to examine the functions of the RES by assimilate colloids other than iron colloids, linoleic acid-(14)C emulsion and lipid emulsion, fatgen, were selected and by treating the RES of the dog with these emulsions observations were carried out on the behaviour of the RES functions at the surgical intervention. The results of the study are briefly presented in this communication. 1. It was fund that linoleic acid (14)C-emulsion is taken up by the RES, is soon saturated, and readily incorporates into fat tissue. For the study of the RES function in animals this is a very usefuly method with a promising future. 2. The lipid emulsion fatgen is taken up and metabolized readily by the RES, proving that the treatment of RES by this emulsion can take place of Congo red method in the clinical examination of the RES. 3. For the examination of the function of the RES of experimental dogs at surgical operation the treatment by the lipid emulsion gives somewhat different results in detail compared with the Glycyrrhizin acid iron colloid, but in the case of splenectomy the compensatory function of the residual spleen is markedly accelerated and the liver in the splenectomized group compensates the removal of spleen, indicating that both methods yield similar results on the whole. From these findings it seems that the lipid colloid method as well as the Glycyrrhizin iron colloid method are to be highly recommended as the new, excellent methods to be applicable to clinical examinations of the RES functions.
Published Date
1967-04-30
Publication Title
岡山医学会雑誌
Publication Title Alternative
Journal of Okayama Medical Association
Volume
volume79
Issue
issue3-4
Publisher
岡山医学会
Publisher Alternative
Okayama Medical Association
Start Page
387
End Page
396
ISSN
0030-1558
NCID
AN00032489
Content Type
Journal Article
Official Url
https://www.jstage.jst.go.jp/article/joma1947/79/3-4/79_3-4_387/_article/-char/ja/
Related Url
http://www.okayama-u.ac.jp/user/oma/
language
日本語
Copyright Holders
岡山医学会
File Version
publisher
Refereed
True
Eprints Journal Name
joma