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ID 18013
Eprint ID
18013
FullText URL
Thumnail 82_529.pdf 533 KB
Title Alternative
Studies on the Treatment of Malignant Tumors with Fibroblast-inhibiting Agent Part Ⅱ. Effects of the Combined Chemotherapy with Chloroquine and Several Anti-tumor Drugs on Iron Metabolism in Tumor-bearing Animals
Author
Mori, Toshio
Abstract
Studies on iron metabolism, especially on organ iron were performed in mice with Bashford cancer treated by combined administration of chloroquine and several anti-tumor agents. 1) Chloroquine alone tended to inhibit the storage of non-hemin iron in the tumor tissues or organs. 2) No definite tendency was shown in the storage of non-hemin iron following administration of anti-tumor agents alone. 3) Generally, it was difficult to find a definite tendency in organs such as the liver and spleen after combined administration, but in the tumors the storage of non-hemin iron (γ/g) tended to be more inhibited by combineda dministration than in controls and in mice treated by anti-tumor drugs alone. 4) These data suggest that the combined chemotherapy with choroquine and several antitumor drugs exhibits more effective anti-tumor activity with respect to iron metabolism of animals bearing Bashford cancer than single administration of anti tumor drugs.
Published Date
1970-12-30
Publication Title
岡山医学会雑誌
Publication Title Alternative
Journal of Okayama Medical Association
Volume
volume82
Issue
issue11-12
Publisher
岡山医学会
Publisher Alternative
Okayama Medical Association
Start Page
529
End Page
538
ISSN
0030-1558
NCID
AN00032489
Content Type
Journal Article
Official Url
https://www.jstage.jst.go.jp/article/joma1947/82/11-12/82_11-12_529/_article/-char/ja/
Related Url
http://www.okayama-u.ac.jp/user/oma/
language
日本語
Copyright Holders
岡山医学会
File Version
publisher
Refereed
True
Eprints Journal Name
joma