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ID 17975
Eprint ID
17975
FullText URL
Thumnail 79_211.pdf 1.99 MB
Title Alternative
Anti-tumor activity of an unsaturated fatty acid extractedfrom rabbit liver irradiation Part. I. Effect on lymphatic ascites leukemia in DBA mice
Author
Watanabe, Terutugu
Abstract
Aanti-tumor activity of OX substance, an unsaturated fatty acid extracted from rabbit liver 24 hours after 3,000γ irradiation, was studied in lymphatic asites leukemia in methyl cholanthren induced DBA mice. OX substance was administered intravenoulsy from the tail vein of mice. Red blood cell and white blood cell count of the peripheral blood, character of ascites and morphalogical changes of ascites cells, pathalogical findings of the visceral organs, body weight and survival period of mice were observed and following results were obtained. 1) Administration of OX substance gave arise prevention of anemia and suppression of development of leukemia in DBA mice with ascites leukemia. 2) OX substance gave no influence to changes of the body weight of DBA mice with acites leukemia. 3) Life span of DBA mice was remarkably prolonged by OX substance administration. 4) OX substance inhibited the infiltration of leukemia cells in the lung, liver, spleen and other organs of DBA mice. 5) OX substznce schowed the strong cytotoxic effect on the ascites leukemia cells in DBA mice.
Published Date
1967-04-30
Publication Title
岡山医学会雑誌
Publication Title Alternative
Journal of Okayama Medical Association
Volume
volume79
Issue
issue3-4
Publisher
岡山医学会
Publisher Alternative
Okayama Medical Association
Start Page
211
End Page
217
ISSN
0030-1558
NCID
AN00032489
Content Type
Journal Article
Official Url
https://www.jstage.jst.go.jp/article/joma1947/79/3-4/79_3-4_211/_article/-char/ja/
Related Url
http://www.okayama-u.ac.jp/user/oma/
language
日本語
Copyright Holders
岡山医学会
File Version
publisher
Refereed
True
Eprints Journal Name
joma