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ID 17650
Eprint ID
17650
FullText URL
Thumnail 88_709.pdf 309 KB
Title Alternative
Effects of insulin on phenylketonuria Part 2. Effects on free amino acids im serum
Author
Okita, Misako
Abstract
1. 対照正常人6例とPKU患者6例について,インスリン投与前と投与120分後の血中遊離アミノ酸の変化を検討した. 2. 対照正常人では, Aspが2例で増加したほかはすべてのアミノ酸が減少し, Met, Leu, Arg, Ileの順に減少率が大であった. 3. PKU患者では, Pheは4例, Tyrは全例で減少した. 4. PKU患者でGlu, Asp, Arg, His, Tau, Trp, Orn, Proの増加例があった.
Abstract Alternative
Free amino acids in sera after insulin injection were studied using six PKU subjects and six normal subjects. Blood samples were collected prior to the insulin injection and 120 minutes after insulin injection. The results were as follows; 1. Serum free amino acid level of normal subjects except aspartic acid level were all decreased after insulin injection. 2. Serum levels of free tyrosine, leucine, isoleucine, valine, alanine, glutamic acid, threonine, arginine, lysine and proline of PKU subjects were significantly lower than normal level. 3. Phenylalanine level is decreased in four PKU cases 120 minutes after insulin injection. Tyrosine level decreased in all PKU cases 120 minutes after insulin injection. 4. The levels of glutamic acid (4 cases), aspartic acid (3 cases), proline (2 cases), tryptophan (1 case), taurine (1 case), arginine (1 case), histidine (1 case) and ornithine (1 case) of PKU subjects were increased after insulin injection.
Published Date
1976-10-30
Publication Title
岡山医学会雑誌
Publication Title Alternative
Journal of Okayama Medical Association
Volume
volume88
Issue
issue9-10
Publisher
岡山医学会
Publisher Alternative
Okayama Medical Association
Start Page
709
End Page
716
ISSN
0030-1558
NCID
AN00032489
Content Type
Journal Article
Official Url
https://www.jstage.jst.go.jp/article/joma1947/88/9-10/88_9-10_709/_article/-char/ja/
Related Url
http://www.okayama-u.ac.jp/user/oma/
language
日本語
Copyright Holders
岡山医学会
File Version
publisher
Refereed
True
Eprints Journal Name
joma