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ID 17582
Eprint ID
17582
FullText URL
Thumnail 88_275.pdf 447 KB
Title Alternative
Radioimmunoassay of Serum α-Fetiprotein Concentration and Its Alteration during the Course of Hepatitis and Liver Cirrhosis
Author
Tanaka, Yoshikiyo
Abstract
Serum α-fetoprotein concentration were compared with the alteration of serum GPT activity in patients with acute hepatitis, patient with fluminant hepatitis, patients with subacute hepatitis, patients with chronic hepatitis (active form), patients with chronic hepatitis with sublobular hepatic necrosis, patients with A type of liver cirrhosis and patients with A'type of liver cirrhosis. Time course of serum α-fetoprotein concetration and serum GPT activity were clasified into the following 6 types.: Type 1. the peak of serum α-fetoprotein concentration comes after peak of serum GPT activity. Type 2. both peaks overlaps with each other in terms of temporal alteration. Type 3. a peak elevation in serum α-fetoprotein concentration with flat moderately increased level of serum GPT activity. Type 4. both levels activity flucutuation without peak at increased levels. Type 5. a peak elevation in serum GPT activity without serum α-fetoprotein peak. Type 6. progressive increase in serum α-fetoprotein concentration over 2000 ng/ml with or without similar serum GPT activity increase. Type 1 and 2 were frequently observed in case of acute hepatitis, subacute hepatitis and chronic hepatitis. Type 3 and 4 were rather specific to liver cirrhosis. Type 5 was frequently observed in acute hepatitis and chronic hepatitis with sublobular hepatic necrosis. Type 6 was observed in hepatocellular carcinoma.
Published Date
1976-04-30
Publication Title
岡山医学会雑誌
Publication Title Alternative
Journal of Okayama Medical Association
Volume
volume88
Issue
issue3-4
Publisher
岡山医学会
Publisher Alternative
Okayama Medical Association
Start Page
275
End Page
283
ISSN
0030-1558
NCID
AN00032489
Content Type
Journal Article
Official Url
https://www.jstage.jst.go.jp/article/joma1947/88/3-4/88_3-4_275/_article/-char/ja/
Related Url
http://www.okayama-u.ac.jp/user/oma/
language
日本語
Copyright Holders
岡山医学会
File Version
publisher
Refereed
True
Eprints Journal Name
joma