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ID 17528
Eprint ID
17528
FullText URL
Thumnail 85_1.pdf 4.64 MB
Title Alternative
Studies on the treatment of malignant tumors with fibroblast-inhibiting agents Part Ⅰ. Effects of chloroquine on agar granulomas
Author
Shibuya, Koichi
Abstract
Effects of intravenous administration of various chloroquine derivatives (chloroquine diphosphate, chloroquine diorotate, chloroquine chondroitin sulfate and chloroquine polygalacturonate) on rat agar granulomas were studied and the following conclusions were obtained. 1) The weight of agar granulomas was reduced with all four chloroquine derivatives in comparison to that of controls. 2) Histologically, the capsule formation and connective tissue element of agar granulomas were poor in rats given chloroquine. 3) The above findings suggest that chloroquine has affinity to fibroblasts and acts to be inhibitory to these cells.
Published Date
1973-02-28
Publication Title
岡山医学会雑誌
Publication Title Alternative
Journal of Okayama Medical Association
Volume
volume85
Issue
issue1-2
Publisher
岡山医学会
Publisher Alternative
Okayama Medical Association
Start Page
1
End Page
7
ISSN
0030-1558
NCID
AN00032489
Content Type
Journal Article
Official Url
https://www.jstage.jst.go.jp/article/joma1947/85/1-2/85_1-2_1/_article/-char/ja/
Related Url
http://www.okayama-u.ac.jp/user/oma/
language
日本語
Copyright Holders
岡山医学会
File Version
publisher
Refereed
True
Eprints Journal Name
joma