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ID 17287
Eprint ID
17287
FullText URL
Thumnail 90_515.pdf 2.01 MB
Title Alternative
Studies on anticomplementary activity in systemic lupus erythematosus: Part 1. Clinical studies
Author
Amano, Tetsuki
Abstract
The anticomplementary activity (ACA) of the sera from systemic lupus erythematosus (SLE) patients was measured by the modified Wasserman-Levine's method, and the following results were obtained. 1. The sera from SLE, liver cirrhosis, Hashimoto disease and rheumatoid arthritis patients revealed high ACA. 2. In SLE, ACA of the sera with high concentration of γ-Gl or IgG was significantly higher than those of the sera with low concentration of it. 3. There was no correlation between ACA and serum complement level in SLE, but ACA was rather high in hypocomplementemic sera. 4. ACA of the sera that showed the shaggy pattern was especially high among the sera showing various ANF patterns, and ACA correlated with the level of anti-DNA antibody in SLE. 5. ACA was significantly high in sera with high level of rheumatoid factor in SLE. 6. ACA in SLE varied with activities of lupus nephritis. These data may suggest that positive ACA shows the exsistence of the circulating immune complexes in SLE sera, and the measurement of ACA is important to know the prognosis of SLE.
Published Date
1978-06-30
Publication Title
岡山医学会雑誌
Publication Title Alternative
Journal of Okayama Medical Association
Volume
volume90
Issue
issue5-6
Publisher
岡山医学会
Publisher Alternative
Okayama Medical Association
Start Page
515
End Page
525
ISSN
0030-1558
NCID
AN00032489
Content Type
Journal Article
Official Url
https://www.jstage.jst.go.jp/article/joma1947/90/5-6/90_5-6_515/_article/-char/ja/
Related Url
http://www.okayama-u.ac.jp/user/oma/index.html
language
日本語
Copyright Holders
岡山医学会
File Version
publisher
Refereed
True
Eprints Journal Name
joma