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ID 17283
Eprint ID
17283
FullText URL
Thumnail 87_21.pdf 672 KB
Title Alternative
Clinical Studies on Preleukemia Part 1 Clinical Studies on Preleukemic Cases in Japan
Author
Takahashi, Isao
Abstract
Preleukemia is defined as a hematological disorder preceding the clinical recognition of leukemia. Up to now, some cases of preleukemia have reported. However, systematic studies on preleukemia have been rare. This paper describes clinical data of 62 cases of preleukemia in Japan, which may be summarized as follows. 1. Hypoplastic anemia-like hematological disorder (hypoplastic preleukemic stage) was the most frequent type among various preleukemic disorders (41 of 62 cases). Secondly, dyserythropoietic conditions, including pernicious anemia and sideroblastic anemia, were seen in preleukemic disorders (8 of 62 cases). 2. Preleukemia tended to occur in rather elderly males. This tendency was also recognized in hypoplastic preleukemic cases. 3. Preleukemic stages tended to persist for a relatively long period and survival times from the point of diagnosis of leukemia were relatively short. 4. Fifty-one of 62 cases terminated into acute lekemia, of which 31 cases were acute myelocytic leukemia, 7 cases monocytic leukemia, 5 cases acute lymphocytic leukemia, 2 cases acute erythroleukemia, 6 cases unknown type. Chronic leukemia was seen only in 6 cases of 62 cases and they were all myelocytic. Particularly, all hypoplastic preleukemic cases, excluding 4 unknown cases, terminated into acute leukemia. 5. The appearance of erythroblasts in the peripheral blood, a slight increase of myeloblasts and a relative erythroid hyperplasia in the bone marrow were noted at the hypoplastic preleukemic stage. On the other hand, some of hypolastic preleukemic cases tended to show aleukemic finding and hypocellular marrow at the time of diagnosis of leukemia.
Published Date
1975-02-28
Publication Title
岡山医学会雑誌
Publication Title Alternative
Journal of Okayama Medical Association
Volume
volume87
Issue
issue1-2
Publisher
岡山医学会
Publisher Alternative
Okayama Medical Association
Start Page
21
End Page
31
ISSN
0030-1558
NCID
AN00032489
Content Type
Journal Article
Official Url
https://www.jstage.jst.go.jp/article/joma1947/87/1-2/87_1-2_21/_article/-char/ja/
Related Url
http://www.okayama-u.ac.jp/user/oma/
language
日本語
Copyright Holders
岡山医学会
File Version
publisher
Refereed
True
Eprints Journal Name
joma