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ID 17061
Eprint ID
17061
FullText URL
Thumnail 89_65.pdf 643 KB
Title Alternative
Clinical studies of the role of IgE in allergic and collagen diseases Part I Determination and pathogenic significance of IgE in sera, synovial fluid and urine
Author
Ooguchi, Yoshito
Abstract
IgE concentrations in sera, synovial fluid and urine were measured from patients with allergic and collagen diseases. The following results were obtained. 1) Significantly high serum IgE levels were found in asthma patients compared to normal controls. Furthermore, serum IgE levels were significantly higher in groups with atopic or mixed asthma than in the group with infectious asthma. 2) Serum IgE levels of urcicaria patients were normal. One case of penicillin-induced urcicaria had 1350ng/ml. 3) The mean serum IgE level of RA patients not treated by gold therapy tended to be low. RA patients who showed side effects to gold therapy frequently indicated high serum IgE levels. 4) The mean serum IgE level of SLE patients was slightly higher than normal controls. No relationships were found between the IgE levels and ANF stainning patterns in SLE patients. 5) Serum IgE levels were similar in patients with Behcet disease, Polymyositis and in normal controls. One PSS patient had a remarkably elevated serum IgE level. 6) Studies of IgG, IgA and IgE levels in synovial fluid of RA patients indicated the possibility that IgG and IgM were synthesized in the local joint cavity and that IgE was consumed locally in the joint cavity. 7) In studies of levels of immunoglobulins in urine of proteinuria patients, most urinary IgE was estimated to be locally produced in the urinary tract between the collecting tubes and bladder.
Published Date
1977-02-28
Publication Title
岡山医学会雑誌
Publication Title Alternative
Journal of Okayama Medical Association
Volume
volume89
Issue
issue1-2
Publisher
岡山医学会
Publisher Alternative
Okayama Medical Association
Start Page
65
End Page
78
ISSN
0030-1558
NCID
AN00032489
Content Type
Journal Article
Official Url
https://www.jstage.jst.go.jp/article/joma1947/89/1-2/89_1-2_65/_article/-char/ja/
Related Url
http://www.okayama-u.ac.jp/user/oma/index.html
language
日本語
Copyright Holders
岡山医学会
File Version
publisher
Refereed
True
Eprints Journal Name
joma