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ID 17022
Eprint ID
17022
FullText URL
Thumnail 92_359.pdf 371 KB
Title Alternative
Studies on bile acid and bilirubin in liver diseases Part 2. Clinical significance of serum bilirubin sulfate in various liver diseases
Author
Ishikawa, Yasusuke
Abstract
The clinical significance of serum bilirubin sulfate, one of the direct bilirubin, was evaluated in various liver diseases with over 2 mg/dl of serum bilirubin concentration. The diagnosis included 25 cases of acute hepatitis, 8 cases of chronic hepatitis, 8 cases of liver cirrhosis and 16 cases of liver cirrhosis with hepatoma. Bilirubin sulfate was fractioned by Yonei's solvent partition method. The clinical significance of bilirubin sulfate was assessed by comparison of bilirubin sulfate with the other bilirubin fractions and with non-specific liver function tests. The results were as follows; 1) The existence of bilirubin sulfate was confirmed in human sera. Bilirubin sulfate concentration correlated with serum total bilirubin and direct bilirubin, and the correlation with direct bilirubin was higher than total bilirubin. 2) The percentage of bilirubin sulfate in total and direct bilirubin increased in the order of acute hepatitis, chronic hepatitis and liver cirrhosis. The percentage of bilirubin sulfate was higher in direct bilirubin than in total bilirubin. 3) Bilirubin sulfate showed the following correlation with non-specific liver function tests; with cholesterol in acute hepatitis, with choline esterase in chronic hepatitis and with GOT, cholesterol and bile acid in liver diseases.
Keywords
各種肝疾患
血清硫酸抱合型Bilirubin
一般肝機能検査
血清胆汁酸
Published Date
1980-04-30
Publication Title
岡山医学会雑誌
Publication Title Alternative
Journal of Okayama Medical Association
Volume
volume92
Issue
issue3-4
Publisher
岡山医学会
Publisher Alternative
Okayama Medical Association
Start Page
359
End Page
366
ISSN
0030-1558
NCID
AN00032489
Content Type
Journal Article
Official Url
https://www.jstage.jst.go.jp/article/joma1947/92/3-4/92_3-4_359/_article/-char/ja/
Related Url
http://www.okayama-u.ac.jp/user/oma/index.html
language
日本語
Copyright Holders
岡山医学会
File Version
publisher
Refereed
True
Eprints Journal Name
joma