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ID 16448
Eprint ID
16448
FullText URL
Thumnail 95_1347.pdf 2.58 MB
Title Alternative
Effect of extracorporeal circulation on myocardial myosin adenosine triphosphatase activity-A comparative study between dogs with and without aortic cross clamping and left ventricular hypertrophy
Author
Shiba, Kazushige
Abstract
The effect of extracorporeal circulation (ECC) on myocardial myosin adenosine triphosphatase (ATPase) activity was studied in 23 dogs with normal heart and 17 dogs with left ventricular hypertrophy. Intermittent aortic cross clamping for 60 minutes was done in some dogs and not in others during ECC. The cardiac functions and myocardial ATPase activity before and 60 minutes after ECC were compared. Cardiac function was depressed in dogs undergoing aortic cross clamping, especially in those with hypertrophied heart after ECC. It was observed that cardiac myosin ATPase activity was diminished in dogs with hypertrophied left ventricles. In the other dogs, no remarkable changes were observed in the myosin ATPase activity. It was concluded that myosin ATPase activity was depressed during aortic cross clamping in dogs with hypertrophied left ventricles and that the disturbance of energy utilization in the myocardium was one of the causes of depressed cardiac function after ECC.
Keywords
体外循環
大動脈遮断
左室肥大心
ミオシンATPase
Published Date
1983-12-30
Publication Title
岡山医学会雑誌
Publication Title Alternative
Journal of Okayama Medical Association
Volume
volume95
Issue
issue11-12
Publisher
岡山医学会
Publisher Alternative
Okayama Medical Association
Start Page
1347
End Page
1358
ISSN
0030-1558
NCID
AN00032489
Content Type
Journal Article
Official Url
https://www.jstage.jst.go.jp/article/joma1947/95/11-12/95_11-12_1347/_article/-char/ja/
Related Url
http://www.okayama-u.ac.jp/user/oma/index.html
language
日本語
Copyright Holders
岡山医学会
File Version
publisher
Refereed
True
Eprints Journal Name
joma