このエントリーをはてなブックマークに追加
ID 16228
Eprint ID
16228
FullText URL
Thumnail 97_937.pdf 408 KB
Title Alternative
Salt-tolerance mechanism of Staphylococcus aureus -Dynamic aspects on proline contributing in osmoregulation.
Author
Nagamachi, Eiko
Tomochika, Ken-ichi
Hirai, Yoshikazu
Maruyama, Takashi
Okabe, Akinobu
Kanemasa, Yasuhiro
Abstract
S. aureus can grow in high salinity condition by a salt-tolerance mechanism. We have shown that S. aureus accumulated a large amount of proline in cytoplasm for the osmoregulation in high osmotic condition. In this study, we tried to elucidate the dynamics of proline by altering the salt concentration and supplementing proline in semisynthetic or synthetic media. S. aureus required only 20μM of proline as an essential amino acid under the normal condition, but 700μM to accumulate proline as an osmoregulator under the 10% NaCl condition. When the supplementary proline was not enough, S. aureus accumulated glutamine to compensate the osmoregulation by proline.
Keywords
Staphylococcus aureus
salt-tolerance
osmoregulation
proline
Published Date
1985-12-30
Publication Title
岡山医学会雑誌
Publication Title Alternative
Journal of Okayama Medical Association
Volume
volume97
Issue
issue11-12
Publisher
岡山医学会
Publisher Alternative
Okayama Medical Association
Start Page
937
End Page
946
ISSN
0030-1558
NCID
AN00032489
Content Type
Journal Article
Official Url
https://www.jstage.jst.go.jp/article/joma1947/97/11-12/97_11-12_937/_article/-char/ja/
Related Url
http://www.okayama-u.ac.jp/user/oma/index.html
language
日本語
Copyright Holders
岡山医学会
File Version
publisher
Refereed
True
Eprints Journal Name
joma