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ID 16013
Eprint ID
16013
FullText URL
Thumnail 99_1189.pdf 438 KB
Title Alternative
Studies on aortic medial smooth muscle cell culture Part 1. The effects of lipid peroxides on cell proliferation in cells derived from aged or diabetic rats
Author
Ishioka, Tatsuji
Abstract
The cultured smooth muscle cell offers several advantages to investigation of cell character. It can be utilized to make studies on aging and atherosclerosis. This work was carried out to investigate the effects of intracellular lipid peroxides and aging on the growth rate of cultured aortic medial smooth muscle cells obtained from normal rats and rats with streptozotosin-induced rats. Cells from young and old rats showed similar growth and contained the same amount of intracellular lipid peroxides. However the rate of growth of cells from diabetic rats was inversely proportional to the period of illness and also to the quantity of lipid peroxides contained in the cells. When normal cells were cultured in an adriamycin-containing medium, their growth rate was inversely proportional to the adriamycin concentration of the medium and also the amount of intracellular lipid peroxides.
Keywords
過酸化脂質
大動脈中膜平滑筋培養
糖尿病
加齢
Published Date
1987-10-31
Publication Title
岡山医学会雑誌
Publication Title Alternative
Journal of Okayama Medical Association
Volume
volume99
Issue
issue9-10
Publisher
岡山医学会
Publisher Alternative
Okayama Medical Association
Start Page
1189
End Page
1196
ISSN
0030-1558
NCID
AN00032489
Content Type
Journal Article
Official Url
https://www.jstage.jst.go.jp/article/joma1947/99/9-10/99_9-10_1189/_article/-char/ja/
Related Url
http://www.okayama-u.ac.jp/user/oma/index.html
language
日本語
Copyright Holders
岡山医学会
File Version
publisher
Refereed
True
Eprints Journal Name
joma