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ID 15949
Eprint ID
15949
FullText URL
Thumnail 99_725.pdf 2.61 MB
Title Alternative
Morphological and functional analysis of basophils in chronic myelocytic leukemia (CML) 1. Clinical evaluation of basophils with special reference to the basophilogram in the early diagnosis of blastic crisis
Author
Fujimoto, Shuitsu
Abstract
The pathophysiologic role of basophils in CML has not been fully elucidated. In order to establish criteria for the early diagnosis of blastic crisis in CML and also to gain some information about the maturation of basophils in CML, the author observed light-microscopically the morphologic changes of basophils in CML using so-called basophilograms. Types I and II basophils in the basophilograms corresponded to mature basophils, whereas types III and IV corresponded mostly to immature cells (r=0.65, p<0.01). Type III and IV basophils amounted to more than 60% of all basophils in the blastic phase of CML. These findings indicated that the basophilogram is useful in the early diagnosis of blastic crisis in CML.
Keywords
chronic myelocytic leukemia
basophils
early diagnosis of blastic crisis
Published Date
1987-08-30
Publication Title
岡山医学会雑誌
Publication Title Alternative
Journal of Okayama Medical Association
Volume
volume99
Issue
issue7-8
Publisher
岡山医学会
Publisher Alternative
Okayama Medical Association
Start Page
725
End Page
736
ISSN
0030-1558
NCID
AN00032489
Content Type
Journal Article
Official Url
https://www.jstage.jst.go.jp/article/joma1947/99/7-8/99_7-8_725/_article/-char/ja/
Related Url
http://www.okayama-u.ac.jp/user/oma/index.html
language
日本語
Copyright Holders
岡山医学会
File Version
publisher
Refereed
True
Eprints Journal Name
joma