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ID 15859
Eprint ID
15859
FullText URL
100_97.pdf 5.33 MB
Title Alternative
Antigenicity of bacterial membrane-cardiolipin and reactivity of anti-cardiolipin antibody with bacteria and DNA
Author
Nakamura, Tomoaki
Abstract
I investigated the possibility of production of antibody to bacterial membrane-cardiolipin using cardiolipin micelles, Staphylococcus aureus (S.aureus) and L-form of S. aureus. I also investigated and the reactivity of anti-cardiolipin (CL) antibody with bacteria and DNA.I confirmed that the bacterial membrane-cardiolipin induced the production of anti-CL antibody, which was present mainly in the IgM fraction, but also in the IgG fraction.The anti-CL antibody reacted with L-form of bacteria and bacterial membrane fractions, but it did not react with the vegetative form of bacteria other than S. aureus nor with DNA. On the basis of these findings, I considered that the L-form of bacteria or fragments of bacterial membranes can be detected by immunofluorescence antibody technique or nitrocellulose membrane-enzyme immunoassay using the anti-CL antibody.
Keywords
カルジオリピン
抗カルジオリピン抗体
抗細菌細胞膜抗体
L型菌
抗DNA抗体
Published Date
1988
Publication Title
岡山医学会雑誌
Publication Title Alternative
Journal of Okayama Medical Association
Volume
volume100
Issue
issue1-2
Publisher
岡山医学会
Publisher Alternative
Okayama Medical Association
Start Page
97
End Page
106
ISSN
0030-1558
NCID
AN00032489
Content Type
Journal Article
Official Url
https://www.jstage.jst.go.jp/article/joma1947/100/1-2/100_1-2_97/_article/-char/ja/
Related Url
http://www.okayama-u.ac.jp/user/oma/index.html
language
日本語
Copyright Holders
岡山医学会
File Version
publisher
Refereed
True
Eprints Journal Name
joma