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ID 14911
Eprint ID
14911
FullText URL
Title Alternative
A case of systemic lupus erythematosus (SLE) associated with disseminated intravascular coagulation (DIC)
Author
Okamoto, Makoto
Tsugeno, Hirofumi
Harada, Seishi
Hosaki, Yasuhiro
Mifune, Takashi
Tanizaki, Yoshiro
Niiya, Kenji
Harada, Mine
Abstract
播種性血管内凝固症候群(DIC)を合併した全身性エリテマトーデス(SLE)を経験したので報告する。症例は73歳女性。64歳時慢性関節リウマチ(RA)と診断された。1999年1月食欲低下を訴え当科受診した。血小板減少、FDP高値、PT上昇等よりDIC発症を疑った。膠原病では凝固系の異常を認めるが、本症例では凝固系が完進しDICを来したと考えられた。 本症例はリウマチ因子陽性であったが、朝のこわばり等典型的なRAの所見に乏しく他の膠原病の合併を疑い、腎障害、血小板減少、抗Sm抗体、抗核抗体陽性よりSLEと診断した。
Abstract Alternative
A case of disseminated intravascular coagulation (DIC) in a patient with systemic lupus erythematosus (SLE) was described. A 73-year-old female was diagnosed as having rheumatoid arthritis when she was 64 years old. In Jan, 1999, the patient was admitted to our hospital with the complaint of loss of appetite. She was suspected of DIC because of thrombocytopenia, increased fibrin degradation product and prolonged prothrombin test. Abnormality in coagulation system is recognized in collagen disease. In this case coagulation system was activated and DIC occurred. In this case rheumatoid factor was positive. But she was suspected of complicating other collagen disease because she was poor in typical characteristics of rheumatoid arthritis, such as morning stiffness. SLE was diagnosed on the basis of renal injury, thrombocytopenia, positive anti-Sm antibody and positive antinuclaer antibody in this case.
Keywords
慢性関節リウマチ (Rheumatoid arthritis)
全身性エリテマトーデス (Systemic lupus erythematosus)
播種性血管内凝固症候群 (Disseminated intravascular coagulation syndrome)
Published Date
2001-02-01
Publication Title
岡大三朝分院研究報告
Publication Title Alternative
Annual reports of Misasa Medical Branch, Okayama University Medical School / Misasa Medical Center, Okayama University Medical School
Volume
volume71
Publisher
岡山大学医学部附属病院三朝分院
Publisher Alternative
Misasa Medical Branch, OKayama University Medical School
Start Page
68
End Page
72
ISSN
0918-7839
NCID
AN10430852
Content Type
Departmental Bulletin Paper
language
日本語
OAI-PMH Set
岡山大学
File Version
publisher
Refereed
False
Sort Key
9
Eprints Journal Name
mmc