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ID 14788
Eprint ID
14788
FullText URL
Title Alternative
肺気腫と喘息のHRCT上のlow attenuation are(LAA)の性質の差。喫煙との関連を含めて
Author
Hosaki, Yasuhiro
Iwagaki, Naofumi
Nagata, Takuya
Fujii, Makoto
Yokoi, Tadashi
Hamada, Masanori
Tanizaki, Yoshiro
Abstract
The low attenuation area (LAA) of the lungs on high resolution computed tomography (HRCT) was evaluated in 20 asthmatics (10 ex-smokers and 10 never-smokers) and 10 patients with pulmonary emphysema (all ex-smokers) by ventilatory function, lung volume, DLco, and a ratio of expiratory LAA/inspiratory LAA. 1 . The % LAA of the lungs on HRCT was significantly larger in patients with pulmonary emphysema(PE) than in those with asthma, but there was not significant difference in % LAA between ex-smokers and never-smokers of asthmatics. 2. A ratio of expiratory Winspiratory LAA was significantly higher in patients with PE than in those with asthma , and the ratio was significantly higher in ex-smokers of asthmatics than in never-smokers (p<0.05). 3 . The difference in % residual volume and % DLco was significant between asthma and PE , and between ex - smokers and never-smokers of asthmatics (% RV : p<0.05, DLco : p<0.05) . 4 . The difference in the values of % FVC, % FEV(1) .O, and FEV1.0% was significant between asthma and PE, but not significant between ex-smokers and never- smokers of asthmatics. The results suggest that the difference in a ratio of expiratory W inspiratory LAA, % RV and % DLco was significant between ex - smokers and never - smokers of asthmatics , and cigarette smoking induces more irreversible changes of the lungs.
Abstract Alternative
気管支喘息20例(10例:喫煙例,10例非喫煙例)および肺気腫10例(全例喫煙例)を対象に,high resolution computed tomography(HRCT)上の肺のlow attenuation area(LAA)の臨床的意義に ついて検討を加えた。 1.HRCT上の肺の% LAAは,肺気腫において気管支喘息に比べ有意に高い値を示したが,気管支喘息の喫煙例と非喫煙例の間には有意に差は見られなかった。 2.呼気LAA/吸気LAA比は,喘息症例に比べ肺気腫症例で有意に高い値を示した。また,喘息の中では,喫煙例で非喫煙例に比べ有意に高い値が示された。 3.% RVおよび% DLcoは,肺気腫と喘息症例との間で,また喘息症例では,喫煙例と非喫煙例の間で有意の差が見られた。 4.% FVC,% FEV1.0およびFEV1.0%値はいずれも.肺気腫と喘息の間では有意の差が見られたが,喘息の喫煙例と非喫煙例の間には有意の差は見られなかった。以上の結果より,肺気腫と喘息の間では全てのパラメーターで有意差が,また喘息の喫煙例と非喫煙例の間では,呼気LAA/吸気LAA比,% RV,% DLcoで有意差が見られることが示唆された。
Keywords
low attenuation area
asthma
pulmonary emphysema
cigarette smoking
Published Date
2004-02-01
Publication Title
岡大三朝医療センター研究報告
Publication Title Alternative
Annual reports of Misasa Medical Center, Okayama University Medical School / Misasa Medical Center, Okayama University Medical School
Volume
volume74
Publisher
岡山大学医学部附属病院三朝医療センター
Publisher Alternative
Okayama University Medical School / Misasa Medical Center, Okayama University Medical School
Start Page
35
End Page
41
ISSN
1348-1258
NCID
AA11840279
Content Type
Departmental Bulletin Paper
language
日本語
File Version
publisher
Refereed
False
Eprints Journal Name
mmc